Results 141 to 150 of about 183,807 (295)

Computer Science as Natural Science: A 3rd Semester Project on Natural Science Bachelor

, 2018
Denne rapport omhandler Computer Science med fokus på, hvordan dette fag kan høre til som Naturvidenskab. Først vil der blive forklaret om den relevante teori bag naturvidenskaben, for at få en forståelse for, hvad der kvalificerer et fag til at være ...
Bek, Lars Morten, Rytter, Jonatan Emil, Pedersen, Emil Møller   +2 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Dynamic Choreographies: Theory And Implementation

, 2017
International audienceProgramming distributed applications free from communication deadlocks and race conditions is complex. Preserving these properties when applications are updated at runtime is even harder.
Giallorenzo, S, Mauro, Jacopo, Dalla Preda, Mila, Giallorenzo, Saverio, Preda, Mila Dalla, Lanese, Ivan, Dalla Preda, M, Gabbrielli, Maurizio, Mauro, J   +8 more
core   +1 more source

Consensus-based methods for distributed systems, blockchain, and voting: a survey

Journal of Information and Telecommunication
Condorcet and Borda first introduced the consensus theory in the eighteenth century when they studied voting systems. Consensus problems have been investigated for a long time in many fields such as economics, sociology, computer science, bioinformatics,
Dai Tho Dang, Dosam Hwang
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Computer system dependability : an introduction [PDF]

More reliance is being placed on computer systems in many applications. Such systems need to be dependable; we must be able to depend on them to provide the required level of service without failure.
Lord, Andrew M.
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Data Science Employment Classification using Machine Learning

, 2019
Following the gold rush in artificial intelligence, a new career track called "data scientists” has taken the world by storm. With a combination of skills in business intuition and technical soundness, data science is considered the most sought after job
Chandrashekar, Tejus
core   +1 more source

Modern Transformations of Economics: Neuroeconomics

Theory, Methodology, Practice, 2016
Traditionally, economists have not been interested in the neural underpinnings of human behavior. According to the classical decision-making theory, a decision-maker is a perfectly rational cognitive agent ignoring the influence of emotions.
Tatevik Mkrtchyan
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source