Results 161 to 170 of about 5,144,087 (289)

FluoRender Script: A Case Study of Lingua Franca in Translational Computer Science. [PDF]

Comput Sci Eng, 2022
Wan Y, Holman HA, Hansen C.
europepmc   +1 more source

Misconceptions and Computer Science [PDF]

, 2009
Larsen, Bradford
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

CS-KG 2.0: A Large-scale Knowledge Graph of Computer Science. [PDF]

Sci Data
Dessí D, Osborne F, Buscaldi D, Reforgiato Recupero D, Motta E.   +4 more
europepmc   +1 more source

An embedding approach for analyzing the evolution of research topics with a case study on computer science subdomains. [PDF]

Scientometrics, 2023
Taher Harikandeh SR, Aliakbary S, Taheri S.   +2 more
europepmc   +1 more source

Computer Science Without Computers

, 2015
L’informatique a la fâcheuse réputation d’être la science des ordinateurs. Nous montrerons ici, à l’inverse, qu’une part non négligeable des concepts et méthodes de la discipline informatique est indépendante du monde des ordinateurs. Nous verrons ainsi qu’on peut faire fonctionner Internet avec des pigeons voyageurs, que l’algorithmique peut accélérer
openaire   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Shape parameters of evolutionary trees in theoretical computer science. [PDF]

Philos Trans R Soc Lond B Biol Sci
Fuchs M.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source