Results 251 to 260 of about 30,070,977 (302)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
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Science, computational science, and computer science

Communications of the ACM, 1993
We describe computational science as an interdisciplinary approach to doing science on computers. Our purpose is to introduce computational science as a legitimate interest of computer scientists.We present a possible foundation for computational science.
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Computer science: the science of and about information and computation

Communications of the ACM, 2002
New computing paradigms present serious challenges for system architecture.
Ruzena Bajcsy, Craig W. Reynolds
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Computer science with the sciences

ACM SIGCSE Bulletin, 2002
The interdisciplinary field of computational science combines simulation, visualization, mathematical modeling, programming, data structures, networking, database design, symbolic computation, and high performance computing with various scientific disciplines.
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Frontiers for computer science in computational science

Proceedings of the 30th annual Southeast regional conference on - ACM-SE 30, 1992
Computational Science (CPLSC) is an emerging discipline characterized by interdisciplinary team efforts and high precision computing. Computer science is just one dimension of this new discipline.We describe the Clemson program focusing on three major issues: (i) what are the foundations of CPLSC, (ii) how are we to educate computer science students in
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Recentering computer science

Communications of the ACM, 2005
The recent decreases of enrollment in computer science programs signal a chasm between our historical emphasis on programming and the contemporary concerns of those choosing careers.
Denning, P., McGettrick, A.D.
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Science and Computing

2015
This chapter discusses teaching science and computing in a primary school setting.
Smith, Malcolm, Flintoft, Liz, Collins, Robert   +2 more
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Computer Science as a Lens on the Sciences:

IEEE/WIC/ACM International Conference on Web Intelligence (WI'07), 2007
Summary form only given. This article trace the growing influence of fundamental ideas from computer science on the nature of research in a number of scientific fields. There is a growing awareness that information processing lies at the heart of the processes studied in fields as diverse as quantum mechanics, statistical physics, nanotechnology ...
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