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Learning objectives for courses in the Department of Computer Science, Oregon State University [PDF]
This document describes the overall learning objectives for courses in the department of computer science at Oregon State ...
Oregon State University. Department of Computer Science
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
On partisan bias in redistricting: computational complexity meets the science of gerrymandering
CoRR, 2019 Disclaimer: The authors were not supported, financially or otherwise, by any political party. The research results reported in this paper are purely scientific and reported as they are without any regard to which political party they may be of help (if at all)
Tanima Chatterjee, Bhaskar DasGupta
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Analysis Of Computational Complexity Theory For Theoretical Computer Science Applications
İlköğretim Online, 2023 Computational Complexity Theory is a fundamental field in Theoretical Computer Science that analyzes the resources required to solve computational problems. It provides a framework for understanding the efficiency and limitations of algorithms, enabling us toclassify problems into different complexity classes based on their inherent difficulty.
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Governing Complexity in World Politics
, 2021 Complexity is the new global ontology for world politics. This article summarizes the characteristics of complexity and its implications for informed US state policy making.
Western, Jon, Haas, Peter M
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Resource analyses for parallel and distributed coordination [PDF]
, 2011 <p>Predicting the resources that are consumed by a program component is crucial for many parallel or distributed systems. In this context, the main resources of interest are execution time, space and communication/synchronisation costs.
Michaelson, G.J. +20 more
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