Results 21 to 30 of about 30,746,315 (244)

Using the e-learning course “Analytic Geometry” in the process of training students majoring in Computer Science and Information Technology [PDF]

open access: yesCTE Workshop Proceedings, 2019
As a result of literature analysis the expediency of free access of bachelors majoring in Computer Sciences and Information Technologies to modern information educational resources, in particular, e-learning courses in the process of studying mathematical disciplines is substantiated.
Oksana M. Hlushak   +2 more
openaire   +2 more sources

Computational Algebraic Geometry as a Computational Science Elective

open access: yesThe Journal of Computational Science Education, 2010
This paper presents a new mathematics elective for an undergraduate Computational Science program. Algebraic Geometry is a theoretical area of mathematics with a long history, often highlighted by extreme abstraction and difficulty. This changed in the 1960’s when Bruno Buchberger created an algorithm that allowed Algebraic Geometers to compute ...
openaire   +2 more sources

Computational Geometry Applications [PDF]

open access: yes, 2018
Computational geometry is an integral part of mathematics and computer science deals with the algorithmic solution of geometry problems. From the beginning to today, computer geometry links different areas of science and techniques, such as the theory ...
Saracevic, Muzafer; Department of computer sciences, University of Novi Pazar, Serbia   +1 more
core   +1 more source

Algebraic geometry and representation theory in the study of matrix multiplication complexity and other problems in theoretical computer science

open access: yesDifferential Geometry and its Applications, 2022
Many fundamental questions in theoretical computer science are naturally expressed as special cases of the following problem: Let $G$ be a complex reductive group, let $V$ be a $G$-module, and let $v,w$ be elements of $V$. Determine if $w$ is in the $G$-orbit closure of $v$.
openaire   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

[Geometry, analysis, and computation in mathematics and applied science]. Progress report [PDF]

open access: yes, 1994
The principal investigators` work on a variety of pure and applied problems in Differential Geometry, Calculus of Variations and Mathematical Physics has been done in a computational laboratory and been based on interactive scientific computer graphics and high speed computation created by the principal investigators to study geometric interface ...
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

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