Results 41 to 50 of about 1,135,334 (304)

Expressiveness of Temporal Query Languages: On the Modelling of Intervals, Interval Relationships and States [PDF]

, 2006
Storing and retrieving time-related information are important, or even critical, tasks on many areas of Computer Science (CS) and in particular for Artificial Intelligence (AI).
C Dyreson, C Freksa, CE Dyreson, CS Jensen, D Dowty, H Gallaire, I Cervesato, J Clifford, J Grant, JF Allen, JF Allen, Juan Carlos Augusto, L Chittaro, LE McKenzie, M Abadi, M Baudinet, M Stonebraker, P Revesz, R Kowalski, R Kowalski, Rodolfo Sabás Gómez, RT Snodgrass, RT Snodgrass   +22 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

The concordance of field-normalized scores based on Web of Science and Microsoft Academic data: A case study in computer sciences

, 2018
In order to assess Microsoft Academic as a useful data source for evaluative bibliometrics it is crucial to know, if citation counts from Microsoft Academic could be used in common normalization procedures and whether the normalized scores agree with the
Bornmann, Lutz, Haunschild, Robin, Hug, Sven, Scheidsteger, Thomas   +3 more
core   +2 more sources

Integrating collaborative tagging and emergent semantics for image retrieval [PDF]

, 2006
Trabajo presentado al Workshop de la 15th International World Wide Conference (WWW) celebrado en Edinburgh (Scotland) del 22 al 23 de mayo de 2006.In this paper, we investigate the combination of collaborative tagging and emergent semantics for improved ...
Aurnhammer, Melanie, Hanappe, Peter, Steels, Luc   +2 more
core   +1 more source

Internet Databases of the Properties, Enzymatic Reactions, and Metabolism of Small Molecules—Search Options and Applications in Food Science

International Journal of Molecular Sciences, 2016
Internet databases of small molecules, their enzymatic reactions, and metabolism have emerged as useful tools in food science. Database searching is also introduced as part of chemistry or enzymology courses for food technology students.
P. Minkiewicz, M. Darewicz, A. Iwaniak, Justyna Bucholska, P. Starowicz, Emilia Czyrko   +5 more
semanticscholar   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Data Linkage Graph: computation, querying and knowledge discovery of life science database networks

Journal of Integrative Bioinformatics, 2007
Summary To support the interpretation of measured molecular facts, like gene expression experiments or EST sequencing, the functional or the system biological context has to be considered. Doing so, the relationship to existing biological knowledge has to be discovered. In general, biological knowledge is worldwide represented in a network of databases.
Patrick Schweizer, Axel Himmelbach, Matthias Lange, Uwe Scholz   +3 more
openaire   +3 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Report on the EU-US Workshop on Large Scientific Databases [PDF]

, 1999
This joint workshop was set up under the auspices of the Joint European Commission/National Science Foundation Strategy Group that met in Budapest in September 1998.
Aloisio, G., Darlington, J., Gagliardi, F., Messina, P., Williams, R.   +4 more
core  

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source