Results 51 to 60 of about 638,283 (276)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Order Invariance on Decomposable Structures

open access: yes, 2016
Order-invariant formulas access an ordering on a structure's universe, but the model relation is independent of the used ordering. Order invariance is frequently used for logic-based approaches in computer science.
Elberfeld, Michael   +2 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Journal of Spatial Information Science [PDF]

open access: yes, 2011
The Journal of Spatial Information Science (JoSIS) is a new international interdisciplinary journal with open access dedicated to publishing original research and review papers related to spatial information science.
Nedjeljko Frančula
core   +3 more sources

Data Linkage Graph: computation, querying and knowledge discovery of life science database networks

open access: yesJournal of Integrative Bioinformatics, 2007
Summary To support the interpretation of measured molecular facts, like gene expression experiments or EST sequencing, the functional or the system biological context has to be considered. Doing so, the relationship to existing biological knowledge has to be discovered. In general, biological knowledge is worldwide represented in a network of databases.
Lange Matthias   +3 more
openaire   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

IEAD: A Novel One-Line Interface to Query Astronomical Science Archives

open access: yes, 2012
In this article I present IEAD, a new interface for astronomical science databases. It is based on a powerful, yet simple, syntax designed to completely abstract the user from the structure of the underlying database.
Delmotte N., Marco Lombardi
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Mining and visualizing uncertain data objects and named data networking traffics by fuzzy self-organizing map [PDF]

open access: yes, 2014
Uncertainty is widely spread in real-world data. Uncertain data-in computer science-is typically found in the area of sensor networks where the sensors sense the environment with certain error.
Guerrero Zapata, Manel, Karami, Amin
core   +1 more source

Quantifying the consistency of scientific databases

open access: yes, 2015
Science is a social process with far-reaching impact on our modern society. In the recent years, for the first time we are able to scientifically study the science itself.
Bajec, Marko   +4 more
core   +3 more sources

Home - About - Disclaimer - Privacy