Results 71 to 80 of about 26,107,313 (262)
Computer Science Concepts - Finite Automata [PDF]
, 2010 This lecture forms part of the "Finite Automata" topic of the Computer Science Concepts module.
Rong Yang +2 more
core
Orthogonal persistence revisited [PDF]
, 2009 The social and economic importance of large bodies of programs and data that are potentially long-lived has attracted much attention in the commercial and research communities.
Graham N. C. Kirby +5 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Computer Science Concepts - Turing Machines [PDF]
, 2010 This lecture forms part of the "Turing Machines" topic of the Computer Science Concepts module.
Rong Yang +2 more
core
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Personal Reflections on 50 Years of Scientific Computing: 1967–2017 [PDF]
, 2017 Computer hardware, software, numerical algorithms, and science and engineering applications are traced for a half century from the author's ...
Watson, Layne T.
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
A UNIX Micro Requirement for Computer Science Majors [PDF]
, 1986 In the fall of 1985, over 230 freshmen majoring in computer science at Virginia Tech purchased microcomputers running the UNIX operating system, because of a vote in spring 1983 by the faculty of the Department of Computer Science to institute a ...
Fox, Edward A., Birch, Sandra E.
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source