Results 31 to 40 of about 2,128,813 (227)
Проблеми державної інформаційної політики: гармонізація міжнародного і національного інформаційного права [PDF]
Розглядаються питання формування державної інформаційної політики України, теорії інформаційного права, правової інформатики у контексті національної та міжнародної інформаційної безпеки.The questions of creation of state information policy of Ukraine ...
Гавловський, Владислав +3 more
core
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Finding Academic Experts on a MultiSensor Approach using Shannon's Entropy
Expert finding is an information retrieval task concerned with the search for the most knowledgeable people, in some topic, with basis on documents describing peoples activities.
Moreira, Catarina, Wichert, Andreas
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Nearness to Local Subspace Algorithm for Subspace and Motion Segmentation [PDF]
There is a growing interest in computer science, engineering, and mathematics for modeling signals in terms of union of subspaces and manifolds. Subspace segmentation and clustering of high dimensional data drawn from a union of subspaces are especially ...
Aldroubi, Akram, Sekmen, Ali
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Simulation as a means of education fundamentalization informatychnoyi [PDF]
Фундаменталізація, що передбачає поглиблення теоретичної, загальноосвітньої та загальнонаукової підготовки, є тенденцією, характерною для вищої професійної освіти Росії в цілому. Т. В.
Поліщук, О.П. +2 more
core
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source

