Results 51 to 60 of about 305,427 (271)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Faithful (meta-)encodings of programmable strategies into term rewriting systems [PDF]

, 2017
Rewriting is a formalism widely used in computer science and mathematical logic. When using rewriting as a programming or modeling paradigm, the rewrite rules describe the transformations one wants to operate and rewriting strategies are used to con ...
Cirstea, Horatiu, Lenglet, Serguei, Moreau, Pierre-Etienne   +2 more
core   +4 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Structure of a File Oriented Programming Language, GPLAN-BL-1 [PDF]

, 1975
Modern computer science has developed languages along many distinct paths; three are: Operating System Languages (e.g., OS/JCL), High Level Procedural Languages (e.g., FORTRAN), and High Level Non-Procedural Data Base Languages (e.g., ALPHA, SQUARE ...
Bonczek, R., Whinston, A.B.
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

PEMBUATAN WEBSITE BERITA D3 ILMU KOMPUTER BERBASIS DESKTOP DAN MOBILE DENGAN PHP DAN MYSQL [PDF]

, 2010
Mahfud Iskandarwanto, 2010. Building Desktop and Mobile News Website at DIII Computer Science with PHP and MYSQL. Diploma Degree Computer Sciences, Mathematics and Siences Faculty, Sebelas Maret University of Surakarta.
ISKANDARWANTO, MAHFUD
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

C-Sheep: Controlling Entities in a 3D Virtual World as a Tool for Computer Science Education [PDF]

, 2006
One of the challenges in teaching computer science in general and computer programming in particular is to maintain the interest of students, who often perceive the subject as difficult and tedious. To this end, we introduce C-Sheep, a mini-language-like
Anderson, Eike F., McLoughlin, L.
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Programming Paradigms in Computer Science Education [PDF]

, 2005
Main styles, or paradigms of programming – imperative, functional, logic, and object-oriented – are shortly described and compared, and corresponding programming techniques are outlined.
Bolshakova, Elena
core