Results 21 to 30 of about 34,521,907 (248)
Ethical Issues in Empirical Studies of Software Engineering [PDF]
, 2002 The popularity of empirical methods in software engineering research is on the rise. Surveys, experiments, metrics, case studies, and field studies are examples of empirical methods used to investigate both software engineering processes and products ...
Singer, Janice A. +3 more
core +1 more source
Fundamental Approaches to Software Engineering [PDF]
, 2018 computer software maintenance; computer software selection and evaluation; formal logic; formal methods; formal specification; programming languages; semantics; software engineering; specifications ...
core +2 more sources
International Seminar on Software Engineering Computer Systems 2011 [PDF]
, 2011 Faculty of Computer Systems & Soft ware Engineering (FSKKP) Universiti Malaysia Pahang (UMP) in collaboration with the Information Society Digital and Wireless Communications (SDIWC) had organized the International Seminar on Software Engineering ...
UMP, .
core +2 more sources
Research and application of clustering algorithm for arbitrary data set [PDF]
, 2008 Paper presented at the 2008 International Conference on Computer Science and Software Engineering, December 12-14, 2008, Wuhan, ChinaThis paper discusses the theory and algorithmic design of the CADD (clustering algorithm based on object density and ...
Song, Yu-Chen +7 more
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Seeing beyond Computer Science and Software Engineering [PDF]
, 2009 The boundaries of computer science are defined by what symbolic computation can accomplish. Software Engineering is concerned with effective use of computing technology to support automatic computation on a large scale so as to construct desirable solutions to worthwhile problems. Both focus on what happens within the machine.
openaire +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source