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International Seminar on Software Engineering Computer Systems 2011 [PDF]

, 2011
Faculty of Computer Systems & Soft ware Engineering (FSKKP) Universiti Malaysia Pahang (UMP) in collaboration with the Information Society Digital and Wireless Communications (SDIWC) had organized the International Seminar on Software Engineering ...
UMP, .
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Summary of the First Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE1)

, 2014
Challenges related to development, deployment, and maintenance of reusable software for science are becoming a growing concern. Many scientists’ research increasingly depends on the quality and availability of software upon which their works are built ...
Ketan Maheshwari, Nancy Wilkins-Diehr, Choi, Sou-Cheng T, Löffler, Frank, Lapp, Hilmar, Venters, Colin, Frank Löffler, Turk, Matthew, Hanwell, Marcus D., Choi, Sou-Cheng T., Hilmar Lapp, Bruce Berriman, Wilkins-Diehr, Nancy, Allen, Gabrielle D., Hetherington, James, Katz, Daniel S, Marcus D Hanwell, Elster, Anne C, James Howison, Anne C Elster, James Hetherington, Swenson, Shel, Sou-Cheng T Choi, Maheshwari, Ketan, Berriman, Bruce, L offler, Frank, Elster, Anne C., Gabrielle D Allen, Shel Swenson, Colin Venters, Daniel S Katz, Katz, Daniel S., Howison, James, Allen, Gabrielle D, Matthew Turk, Hanwell, Marcus D   +35 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Support for evolving software architectures in the ArchWare ADL

, 2011
Software that cannot evolve is condemned to atrophy: it cannot accommodate the constant revision and re-negotiation of its business goals nor intercept the potential of new technology.
Balasubramaniam, Dharini, B. Warboys, B. Snowdon, S. Cimpan, F. Oquendo, Morrison, Ron, Warboys, Brian, K. Mickan, G. Kirby, R.M. Greenwood, Mickan, Kath, Kirby, Graham, Greenwood, Mark, Cîmpan, Sorana, Oquendo, Flavio, Snowdon, Bob, R. Morrison, D. Balasubramaniam   +17 more
core   +1 more source

A pragmatic workflow for research software engineering in computational science

CoRR, 2023
arXiv admin note: text overlap with arXiv:2208 ...
Tomislav Maric, Dennis Gläser, Jan-Patrick Lehr, Ioannis Papagiannidis, Benjamin Lambie, Christian H. Bischof, Dieter Bothe   +6 more
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Advances in Computer Science and Engineering

, 2012
This book includes the proceedings of the second International Conference on Advances in Computer Science and Engineering (CES 2012), which was held during January 13-14, 2012 in Sanya, China.
Zeng, Dehuai
core   +1 more source