Results 131 to 140 of about 913,852 (214)

Frequency controlled energy absorption in parametric mixing. [PDF]

Sci Rep
Chen SC, Yeung LK, Runge K, Deymier PA, Wang YE.   +4 more
europepmc   +1 more source

Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression

Advanced Science, EarlyView.
This study uncovers a new oncogenic mechanism in melanoma. The transcription factor PATZ1 competes with the architectural protein CTCF for DNA binding, thereby disrupting a specific chromatin loop and silencing the tumor suppressor ZBTB20. This event unleashes the pro‐tumorigenic PMEPA1‐p38‐STAT1 signaling axis, promoting cancer progression.
Chaowei Deng, Shuang Cai, Chen Guo, Shaker Khan, Lefan Liu, Qiong Tian, Zhiyuan Ma, Jian Zhang, Lingyu Zhao   +8 more
wiley   +1 more source

Clinical Performance of a Smartphone-Based Sound Amplification Device Versus a Personal Sound Amplification Product in Elders with Mild-to-Moderate Hearing Loss: A Prospective Cohort Study. [PDF]

Medicina (Kaunas)
Wu CJ, Wu SY, Tsai CY, Majumdar A, Yang J, Yang JM, Li LJ.   +6 more
europepmc   +1 more source

Inhibiting cGAS‐STING to Preserve Mitochondrial–Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age‐Related Tendinopathy

Advanced Science, EarlyView.
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang, Weiyong Song, Heng Yin, Yi Wang, Yi Zou, Yuling Li, Yue Luo, Chao Xiang, Xiaoqin Liu, Yan Xiong, Yong Wang, Ke Jiang   +11 more
wiley   +1 more source

Theoretical Analysis, Neural Network-Based Inverse Design, and Experimental Verification of Multilayer Thin-Plate Acoustic Metamaterial Unit Cells. [PDF]

Materials (Basel)
Wang A, Cai C, You Y, Huang Y, Zhan X, Gao L, Zhang Z.   +6 more
europepmc   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

Spatially engineered optical-acoustic matching in quartz-enhanced photoacoustic spectroscopy. [PDF]

Photoacoustics
Cui R, Han W, Wang C, Li C, Ren Y, Li X, Xu J, Spagnolo V, Chen W, Wu H, Dong L.   +10 more
europepmc   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Is there a "mind" behind the music? Attributing music to AI can suppress narrative meaning-making. [PDF]

Cogn Res Princ Implic
Wu SH, Holmes KJ.
europepmc   +1 more source

Advanced Acoustic Technologies for the Monitoring and Management of Sustainable Fisheries: A Practice Manual  [PDF]

, 2019
Aburto-Oropeza, Octavio, Cota-Nieto, Juan José, Erisman, Brad E, López-Sagástegui, Catalina, Rowell, Timothy J   +4 more
core