Results 101 to 110 of about 2,254,385 (285)

Where the Rubber Meets the Sky: Bridging the Gap between Databases and Science [PDF]

IEEE Data Engineering Bulletin, Vol 27.4, Dec. 2004, pp. 3-11, 2005
Scientists in all domains face a data avalanche - both from better instruments and from improved simulations. We believe that computer science tools and computer scientists are in a position to help all the sciences by building tools and developing techniques to manage, analyze, and visualize peta-scale scientific information.
arxiv  

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

Methods of tutoring activities in the training of computer science

Ukrainian Journal of Educational Studies and Information Technology, 2018
The article emphasizes that in the conditions of the reform of the domestic system of education and the Conception of the New Ukrainian School it became possible to formulate an individual program of studying students of a secondary school.
Elvina Bariieva, Tymofii Toporkov
doaj   +3 more sources

Computer simulations in science and engineering - Concepts - Practices - Perspectives [PDF]

arXiv, 2019
The ubiquitous presence of computer simulations in all kinds of research areas evidence their role as the new driving force for the advancement of science and engineering research. Nothing seems to escape the image of success that computer simulations project onto the research community and the general public. One simple way to illustrate this consists
arxiv  

A Literature Review through the Lens of Computer Science Learning Goals Theorized and Explored in Research

Technical Symposium on Computer Science Education, 2017
Research on appropriate topics and goals for computer science (CS) education in elementary and middle school has been ongoing for decades, but the recent movement toward CS for all requires the research community to gain a better understanding of what is
Kathryn M. Rich, Carla Strickland, Diana Franklin   +2 more
semanticscholar   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

PAC Learning, VC Dimension, and the Arithmetic Hierarchy [PDF]

arXiv, 2014
We compute that the index set of PAC-learnable concept classes is $m$-complete $\Sigma^0_3$ within the set of indices for all concept classes of a reasonable form. All concept classes considered are computable enumerations of computable $\Pi^0_1$ classes, in a sense made precise here.
arxiv  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Authorial voice in academic writing: A comparative study of journal articles in English Literature and Computer Science [PDF]

Ibérica, 2020
Academic writers represent themselves in their texts in different ways, notably through use of first person pronouns to construct an authorial voice and enhance arguments.
Yin Ling Cheung , Louwena Lau
doaj