Results 111 to 120 of about 42,732,117 (303)

Computer concepts without computers: a first course in computer science [PDF]

open access: yes, 1997
While some institutions seek to make CS1 curricula more enjoyable by incorporating specialised educational software [1] or by setting more enjoyable programming assignments [2], we have joined the growing number of Computer Science departments that seek ...
Rogers, Bill   +2 more
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

1957-2007: 50 Years of Higher Order Programming Languages

open access: yesJournal of Information and Organizational Sciences, 2009
Fifty years ago one of the greatest breakthroughs in computer programming and in the history of computers happened -- the appearance of FORTRAN, the first higher-order programming language.
Alen Lovrenčić   +2 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Proceedings of the Second Annual Virginia Tech Center for Human-Computer Interaction Research Experience for Undergraduates (REU) Symposium

open access: yes, 2008
Virginia Tech's Center for Human-Computer Interaction presents the project abstracts for the REU ’07 symposium. The REU (Research Experience for Undergraduates) program provides undergraduate students from various universities with the opportunity to ...
Coordinator, REU
core  

Bootstrapping Monte Carlo tree search with an imperfect heuristic

open access: yes, 2012
10.1007/978-3-642-33486-3_11Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)7524 LNAIPART 2164 ...
Lee, W.-S.   +8 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Assessing the relevance of the undergraduate Computer Science curriculum of Nigerian universities: insights from industry

open access: yesОсвітній вимір
This study investigated the degree to which the undergraduate educational programme prepares graduates of Computer Science with significant aptitudes for the working environment; it also examined the degree to which managers rate graduates as having ...
Olabamiji J. Onifade   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy