Results 131 to 140 of about 42,732,117 (303)

Finding Computer Science Syllabi on the World Wide Web [PDF]

open access: yes, 2006
Syllabi contain information useful to students, faculty, and many other people, and given the ubiquity of the WWW many schools are now putting their syllabi online for these people and the general public to access.
Fox, Edward A.   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Readme file for Computer Science Concepts

open access: yes, 2010
This readme file contains details of links to all the Computer Science Concepts module's material held on Jorum and information about the module as well.
Rong Yang   +2 more
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Personal Reflections on 50 Years of Scientific Computing: 1967–2017

open access: yes, 2017
Computer hardware, software, numerical algorithms, and science and engineering applications are traced for a half century from the author's ...
Watson, Layne T.
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Challenges of Computer Science and IT in Teaching-Learning in Saudi Arabia

open access: yesSukkur IBA Journal of Computing and Mathematical Sciences, 2018
Personal Computers (PCs) have invaded all ranges of civilization and there is currently a reasonable connection among technology, development and economic persistence.
Dr. Hafiz Abid Mehmood Malik   +3 more
doaj  

Computer Science Concepts - Complexity

open access: yes, 2010
This lecture forms part of the "Complexity" topic of the Computer Science Concepts module.
Rong Yang   +2 more
core  

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