Results 141 to 150 of about 42,732,117 (303)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

PeerJ Computer Science

PeerJ Computer Science is the open access journal covering all subject areas in computer science, with the backing of a prestigious advisory board and more than 300 academic ...
Silvio Peroni
core   +1 more source

Scientific and Technological Developments in Brain-Computer Interfaces: Dual Bibliometric Analysis of Articles and Patents. [PDF]

JMIR Rehabil Assist Technol
Wang J, Yuan Y, Xu H, Luan G.
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

A Wearable Multimodal Assistive Interface for Virtual Cursor Control in Stroke Survivors with Upper-Limb Impairment. [PDF]

Sensors (Basel)
Liang Y, Zhang L, Jiang Y, Zhu J, Zhao Y, Qin P, Chen D, Peng J, Li Y, Hu X.   +9 more
europepmc   +1 more source

Computer Science Concepts - Introduction

, 2010
This lecture forms part of the "Introduction" topic of the Computer Science Concepts module.
Rong Yang, UKOER, Open Educational Repository in Support of Computer Science   +2 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Development and Clinical Feasibility of a Computer-Assisted Shape Design and Bending System for Spinal Fixation Rods. [PDF]

Med Sci Monit
Li X, Zhang W, Xu Z, Zhao Y, An Y, Li Q, He D.   +6 more
europepmc   +1 more source

Computer Science Concepts - Prolog

, 2010
This lecture forms part of the "Prolog" topic of the Computer Science Concepts module.
Rong Yang, UKOER, Open Educational Repository in Support of Computer Science   +2 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source