Results 221 to 230 of about 44,315,354 (304)

Explainable CNN-BiLSTM Framework for Multi-Class Sleep Apnea Severity Detection Using Single-Lead ECG Signals: A Comprehensive Machine Learning Approach. [PDF]

Diagnostics (Basel)
Al-Quran F, Jawarneh M, Al-Mrayat OI, Ibrahim D, Samara G, Sheta A, Elmarhomy G, Baghdadi NA, Malki A, Atlam ES.   +9 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

RETRACTED: Ali et al. Blockchain-Powered Healthcare Systems: Enhancing Scalability and Security with Hybrid Deep Learning. <i>Sensors</i> 2023, <i>23,</i> 7740. [PDF]

Sensors (Basel)
Ali A, Ali H, Saeed A, Khan AA, Tin TT, Assam M, Ghadi YY, Mohamed HG.   +7 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Taxing the talent that builds American science. [PDF]

Proc Natl Acad Sci U S A
Hegde D.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Hybrid Multi-Domain ECG Feature Learning with mRMR and CNN-Transformer for Cardiac Disease Classification. [PDF]

Bioengineering (Basel)
Alnusayri M, Mumtaz S, Aldughayfiq B, Allahem H, Almashfi N, AlHammadi DA, Jalal A.   +6 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Training Perspectives from the NIH T32 Artificial Intelligence for Precision Nutrition Programs. [PDF]

J Nutr
Mehta S, Huey SL, Massara P, Liu L, Whisner CM, Deng Y, Novotny R, Antwi J, Kim S, Musaad S, Erickson D, Estrin D, Finkelstein JL, Joachims T, Kagemann CH, Tamimi R, Thomas D, Wells MT.   +17 more
europepmc   +1 more source