Results 41 to 50 of about 265,378 (263)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Svetlana Cojocaru (in honour of her 60th anniversary) [PDF]
Computer Science Journal of Moldova, 2012 Our colleague, Vice Editor-in-Chief of the Computer Science Journal of Moldova and director of the Institute of Mathematics and Computer Science of Academy of Sciences of Moldova, dr.hab. Svetlana Cojocaru accomplishes in July a beautiful age.
Editorial board of the "Computer Science Journal of Moldova"
doaj
Efficient enumeration of solutions produced by closure operations [PDF]
Discrete Mathematics & Theoretical Computer Science, 2019 In this paper we address the problem of generating all elements obtained by the saturation of an initial set by some operations. More precisely, we prove that we can generate the closure of a boolean relation (a set of boolean vectors) by polymorphisms ...
Arnaud Mary, Yann Strozecki
doaj +1 more source
Mathematical Logic in Computer Science
CoRR, 2018 The article retraces major events and milestones in the mutual influences between mathematical logic and computer science since the 1950s.
openaire +3 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Applications of computational mathematics in science and engineering [PDF]
International Journal of Computer Mathematics, 2011 We are pleased to offer readers of International Journal of Computer Mathematics this Special Issue consisting of some of the most significant contributions presented at the 9th International Confe...
Jesús Vigo-Aguiar +1 more
openaire +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Approximating Maximum Edge 2-Coloring by Normalizing Graphs [PDF]
Discrete Mathematics & Theoretical Computer ScienceIn a simple, undirected graph G, an edge 2-coloring is a coloring of the edges such that no vertex is incident to edges with more than 2 distinct colors.
Tobias Mömke +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source