Results 111 to 120 of about 3,371,941 (321)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
An application oriented introductory computer science sequence [PDF]
, 1979 James D. Powell
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Applied Computational Intelligence and Soft ComputingAcute lymphoblastic leukemia (ALL) is a type of blood cancer that rapidly impacts the hematologic system, particularly in children, requiring accurate and prompt diagnosis for better clinical outcomes. Manual inspection of peripheral blood smears remains
Aziz Makandar +6 more
doaj +1 more source
EvoSMS: An Event-Oriented Simulation Method for Multi-Core Real-Time Scheduling
Applied SciencesIn this paper, an event-oriented simulation analysis approach was established for the schedulability analysis of multi-core embedded systems. To the best of our knowledge, this work is the first to introduce an event-oriented simulation strategy into ...
Xianchen Shi +3 more
doaj +1 more source
NECESSITY OF LEARNING ANALYTICS IN SOFTWARE ENGINEERING EDUCATION [PDF]
Journal of Engineering Science and Technology, 2015 Computers are necessary and unavoidable part of the modern lifestyle. Software is the key factor to satisfy all the desires and keep up this rock status.
N. PRATHEESH, T. DEVI
doaj
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Advances in Distributed Computing and Artificial Intelligence JournalAs a paradigm shift in network security, the idea of Zero Trust Architecture has attracted a lot of attention recently. This study intends to investigate the assessment and application of Zero Trust Architecture in business networks. Network segmentation,
Pushpendra Kumar Verma +4 more
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