Results 71 to 80 of about 1,325,858 (289)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Evaluating the Effectiveness of Zero Trust Architecture in Protecting Against Advanced Persistent Threats

open access: yesAdvances in Distributed Computing and Artificial Intelligence Journal
As a paradigm shift in network security, the idea of Zero Trust Architecture has attracted a lot of attention recently. This study intends to investigate the assessment and application of Zero Trust Architecture in business networks. Network segmentation,
Pushpendra Kumar Verma   +4 more
doaj   +1 more source

Potential auto-driving threat: Universal rain-removal attack

open access: yesiScience, 2023
Summary: Severe weather conditions pose a significant challenge for computer vision algorithms in autonomous driving applications, particularly regarding robustness.
Jincheng Hu   +7 more
doaj  

Algebraic recognizability of languages [PDF]

open access: yesMathematical Foundations of Computer Science 2004, Tch\`{e}que, R\'{e}publique (2004) 149-175, 2006
Recognizable languages of finite words are part of every computer science cursus, and they are routinely described as a cornerstone for applications and for theory. We would like to briefly explore why that is, and how this word-related notion extends to more complex models, such as those developed for modeling distributed or timed behaviors.
arxiv  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

NECESSITY OF LEARNING ANALYTICS IN SOFTWARE ENGINEERING EDUCATION [PDF]

open access: yesJournal of Engineering Science and Technology, 2015
Computers are necessary and unavoidable part of the modern lifestyle. Software is the key factor to satisfy all the desires and keep up this rock status.
N. PRATHEESH, T. DEVI
doaj  

Comments on "Routh Stability Criterion" [PDF]

open access: yesarXiv, 2010
In this note, we have shown special case on Routh stability criterion, which is not discussed, in previous literature. This idea can be useful in computer science applications.
arxiv  

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

An Optimal Design through a Compound Criterion for Integrating Extra Preference Information in a Choice Experiment: A Case Study on Moka Ground Coffee

open access: yesStats
In this manuscript, we propose an innovative approach to studying consumers’ preferences for coffee, which integrates a choice experiment with consumer sensory tests and chemical analyses (caffeine contents obtained through a High-Performance Liquid ...
Rossella Berni   +2 more
doaj   +1 more source

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