Results 31 to 40 of about 300,117 (216)

Digitally Archiving Architectural Models and Exhibition Designs: The Case of an Art Museum [PDF]

, 2015
[Excerpt] In 2013, a medium-sized art museum located in the Northeast United States received a grant to plan for an electronic records repository. This museum will be referred to here as USAM for brevity.
Cocciolo, Anthony
core   +1 more source

Integration, management and communication of heterogeneous design resources with WWW technologies [PDF]

, 2006
Recently, advanced information technologies have opened new pos-sibilities for collaborative designs. In this paper, a Web-based collaborative de-sign environment is proposed, where heterogeneous design applications can be integrated with a common ...
Ji, S, Li, J, Su, D
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Virtual bloXing - assembly rapid prototyping for near net shapes [PDF]

, 2009
Virtual reality (VR) provides another dimension to many engineering applications. Its immersive and interactive nature allows an intuitive approach to study both cognitive activities and performance evaluation.
Corney, Jonathan, Lim, Theodore, Medellin, Hugo, Ritchie, James, Sung, Raymond   +4 more
core  

Integration of decision support systems to improve decision support performance [PDF]

, 2010
Decision support system (DSS) is a well-established research and development area. Traditional isolated, stand-alone DSS has been recently facing new challenges.
A Kaklauskas, A Kusiak, AC Marquez, AHB Duffy, Alex H. B. Duffy, B Chae, B Lopez, C Carlsson, C Silva, CD Evans, D Lam, D Mladenic, D Riecken, D Thapa, D Zhang, DA Guerra-Zubiaga, DR Dolk, DR Dolk, DS Linthicum, E Claver, E Thomsen, EJM Lauria, F Kebair, FD Turck, G DeSanctis, G Niu, GD Bhatt, GM Carter, H Lan, HA Simon, HA Simon, HA Simon, HY Lin, I Bose, I Boyle, I Thomas, I Truck, Iain M. Boyle, IH Witten, IK Bindoff, J Kolodner, J Zeleznikow, JE Nelson, JF Courtney, JH Lee, JH Lee, JJ Elam, JO Grady, JP Costa, JP Shim, K Eisenhardt, K Kristensen, K Pal, KQ Byung, KW Lee, L Ding, L Ekenberg, L Ekenberg, L Lin, LA Kurgan, M Alvarado, M Beynon, M Bradford, M Cohen, M Frize, M Harrison, M Limayem, M Wang, MJ Huang, MJ Shaw, ML Markus, MN Huhns, N Bolloju, NR Jennings, O Kwon, P Keen, P Keen, PA Rodgers, PC Nutt, QF Ni, R Anderson, R Anson, R Bellazzi, R Chalmeta, R Denzer, R Kimball, R Orwig, R Vahidov, RE Giachetti, RH Rao, Robert Ian Whitfield, RP Baker, RW Blanning, S Daskalaki, S Liu, S Liu, S Liu, S Szykman, SA Raghavan, SB Eom, SD Pinson, Shaofeng Liu, T Bui, TH Davenport, TJ Hess, TP Gerrity, WA Muhanna, WD Li, WD Li, Y Reich, Y Zhu, YC Tsai, Z Shi   +112 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Proposal for a contents design of a graphic engineering lecture [PDF]

, 2019
In this project the subject of Industrial Design from the bachelor’s degree in Industrial Technologies and Economic Analysis of the ETSEIB is reviewed considering the contents and the teaching and evaluating methods.
Andreu Palanca, Alejandro Salvador
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source