Results 101 to 110 of about 1,917,413 (346)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Ontology of genesis of the general education course of Informatics in Russia based on historical and pedagogical analysis

open access: yesRUDN Journal of Informatization in Education
Problem statement. In light of the decisions of the Ministry of Digital Development and Communications and the Ministry of Education of Russian Federation, it is planned to introduce a single textbook on computer science in Russian schools, which ...
Eteri V. Mindzaeva, Natalya I. Ryzhova
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Who participates in computer science education studies? A literature review on K-12 subjects. [PDF]

open access: yesPeerJ Comput Sci, 2021
van der Meulen A   +8 more
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Early virtual reality adopters in Spain: sociodemographic profile and interest in the use of virtual reality as a learning tool

open access: yesHeliyon, 2019
This study describes the social and demographic profile of the first generation of users of marketed virtual reality (VR) viewers in Spain and, subsequently, it assesses the interest in its use as a learning tool.
Roberto Sánchez-Cabrero   +5 more
doaj   +1 more source

Digital Preservation Education in iSchools [PDF]

open access: yes, 2010
This poster investigates digital preservation education in the iSchool caucus. The project identifies core concepts addressed in digital preservation coursework in iSchools and identifies possible areas for curriculum development.
Costello, Kaitlin
core  

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