Results 101 to 110 of about 291,136 (309)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

C-Sheep: Controlling Entities in a 3D Virtual World as a Tool for Computer Science Education

open access: yes, 2006
One of the challenges in teaching computer science in general and computer programming in particular is to maintain the interest of students, who often perceive the subject as difficult and tedious. To this end, we introduce C-Sheep, a mini-language-like
Anderson, Eike F., McLoughlin, L.
core  

Digital storytelling and group work: Integrating the narrative approach into a higher education computer science course

open access: yes, 2019
This study discusses the integration of digital storytelling and the narrative approach into a University level Computer Science course. The pedagogical intervention took place on a project basis.
Korhonen, Ari   +3 more
core   +1 more source

Two perspectives on rebooting computer music education: Composition and computer science [PDF]

open access: yes, 2019
Laptop ensembles and orchestras, in addition to being hubs for collectives of experimental musicians, have become a popular feature in music technology tertiary education curricula. The (short) history of such groups reveals tensions in what these groups
Swift, Ben   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Integration of didactic concepts in using of multi-level mobile computer books of problems in teaching the “Logic” section of school curricula

open access: yesRUDN Journal of Informatization in Education, 2019
Problem and goal. The article actualizes the issues of searching for didactic-methodological bases and their integration in teaching of the “Logic” section within the framework of school curricula of computer science.
Sergey Yurievich Kamyanetsky
doaj   +1 more source

Who participates in computer science education studies? A literature review on K-12 subjects. [PDF]

open access: yesPeerJ Comput Sci, 2021
van der Meulen A   +8 more
europepmc   +1 more source

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