Results 131 to 140 of about 1,449,054 (317)

Protocol for functional screening of CFTR-targeted genetic therapies in patient-derived organoids using DETECTOR deep-learning-based analysis

open access: yesSTAR Protocols
Summary: Here, we present a protocol for the rapid functional screening of gene editing and addition strategies in patient-derived organoids using the deep-learning-based tool DETECTOR (detection of targeted editing of cystic fibrosis transmembrane ...
Mattijs Bulcaen   +7 more
doaj  

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Protocol for building and using a maximum power point output tracker for perovskite solar cells

open access: yesSTAR Protocols
Summary: We recently developed a galvanostatic maximum power point output (MPPT) algorithm for high-hysteresis perovskite solar cells (PSCs), enabling continuous and precise power tracking.
Arturo Sanz-Marco   +3 more
doaj  

2024 Google Scholar Research Interest Ranking for Top 3260 Computer Science Authors [PDF]

open access: yesarXiv
Computer science research spans a diverse array of topics, with scholars exploring numerous subfields. This paper examines the self-reported research interests of the top 3,260 most cited computer science authors on Google Scholar. Using the scholarly Python library, we systematically retrieved and classified their interests into predefined categories ...
arxiv  

The laboratory in a computer science program [PDF]

open access: bronze, 1978
Jerald L. Ripley   +2 more
openalex   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Protocol for characterizing cell motility and extracellular signal-regulated kinase dynamics in epithelial monolayers using FRET imaging data

open access: yesSTAR Protocols
Summary: Extracellular signal-regulated kinase (ERK) activity waves regulate critical processes like wound healing and bacterial pathogen dissemination by altering host cell motility and biomechanics.
Julio Cesar Sanchez-Rendon   +2 more
doaj  

A fundamental computer science course that unifies theory and practice [PDF]

open access: green, 1978
Lawrence Flon   +3 more
openalex   +1 more source

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