Results 41 to 50 of about 659,160 (268)

Protocol for building and using a maximum power point output tracker for perovskite solar cells

STAR Protocols
Summary: We recently developed a galvanostatic maximum power point output (MPPT) algorithm for high-hysteresis perovskite solar cells (PSCs), enabling continuous and precise power tracking.
Arturo Sanz-Marco, Rodrigo Jeronimo-Cruz, Marta Haro, Emilio J. Juarez-Perez   +3 more
doaj   +1 more source

Using the e-learning course “Analytic Geometry” in the process of training students majoring in Computer Science and Information Technology

CTE Workshop Proceedings, 2019
As a result of literature analysis the expediency of free access of bachelors majoring in Computer Sciences and Information Technologies to modern information educational resources, in particular, e-learning courses in the process of studying ...
Oksana M. Hlushak, Volodymyr V. Proshkin, Oksana S. Lytvyn   +2 more
doaj   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Protocol for assessing distances in pathway space for classifier feature sets from machine learning methods

STAR Protocols
Summary: As genes tend to be co-regulated as gene modules, feature selection in machine learning (ML) on gene expression data can be challenged by the complexity of gene regulation.
Bahar Tercan, Victor H. Apolonio, Vinicius S. Chagas, Christopher K. Wong, Jordan A. Lee, Christina Yau, Christopher C. Benz, Joshua M. Stuart, Brian J. Karlberg, Kyle Ellrott, Jasleen K. Grewal, Steven J.M. Jones, Jean C. Zenklusen, A. Gordon Robertson, Peter W. Laird, Andrew D. Cherniack, Mauro A.A. Castro, Theo A. Knijnenberg, Mauro A.A. Castro, Vinicius S. Chagas, Victor H. Apolonio, Verena Friedl, Joshua M. Stuart, Vladislav Uzunangelov, Christopher K. Wong, Rameen Beroukhim, Andrew D. Cherniack, Galen F. Gao, Gad Getz, Stephanie H. Hoyt, Xavier Loinaz, Whijae Roh, Chip Stewart, Lindsay Westlake, Christopher C. Benz, Jasleen K. Grewal, Steven J.M. Jones, A. Gordon Robertson, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Anab Kemal, Roy Tarnuzzer, Peggy I. Wang, Zhining Wang, Liming Yang, Jean C. Zenklusen, Rehan Akbani, Bradley M. Broom, Zhenlin Ju, Andre Schultz, Akinyemi I. Ojesina, Katherine A. Hoadley, Avantika Lal, Daniele Ramazzotti, Chen Wang, Alexander J. Lazar, Lewis R. Roberts, Bahar Tercan, Taek-Kyun Kim, Ilya Shmulevich, Paulos Charonyktakis, Vincenzo Lagani, Ioannis Tsamardinos, Esther Drill, Ronglai Shen, Martin L. Ferguson, Kami E. Chiotti, Kyle Ellrott, Brian J. Karlberg, Jordan A. Lee, Eve Lowenstein, Paul T. Spellman, Adam Struck, Christina Yau, D. Neil Hayes, Toshinori Hinoue, Hui Shen, Peter W. Laird   +78 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Protocol to recover single-cell gene expression profiles from spatial transcriptomics data using cluster computing

STAR Protocols
Summary: Many widely used spatial transcriptomics technologies, such as Visium, capture data at multicellular resolution, precluding single-cell analysis.
Young Je Lee, Hao Chen, Jose Lugo-Martinez   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Protocol for functional screening of CFTR-targeted genetic therapies in patient-derived organoids using DETECTOR deep-learning-based analysis

STAR Protocols
Summary: Here, we present a protocol for the rapid functional screening of gene editing and addition strategies in patient-derived organoids using the deep-learning-based tool DETECTOR (detection of targeted editing of cystic fibrosis transmembrane ...
Mattijs Bulcaen, Ronald B. Liu, Kasper Gryspeert, Sam Thierie, Anabela S. Ramalho, François Vermeulen, Xavier Casadevall I Solvas, Marianne S. Carlon   +7 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Corrigendum: Sources of male and female students' belonging uncertainty in the computer sciences. [PDF]

Front Psychol, 2022
Höhne E, Zander L.
europepmc   +1 more source