Results 51 to 60 of about 2,895,829 (301)

Team

Advances in Distributed Computing and Artificial Intelligence Journal, 2016
ADCAIJ: Advances in Distributed Computing and Artificial Intelligence Journal, 2016, Vol. 5, N. 2, p. I.
Editorial Team
doaj  

Protocol for assessing distances in pathway space for classifier feature sets from machine learning methods

STAR Protocols
Summary: As genes tend to be co-regulated as gene modules, feature selection in machine learning (ML) on gene expression data can be challenged by the complexity of gene regulation.
Bahar Tercan, Victor H. Apolonio, Vinicius S. Chagas, Christopher K. Wong, Jordan A. Lee, Christina Yau, Christopher C. Benz, Joshua M. Stuart, Brian J. Karlberg, Kyle Ellrott, Jasleen K. Grewal, Steven J.M. Jones, Jean C. Zenklusen, A. Gordon Robertson, Peter W. Laird, Andrew D. Cherniack, Mauro A.A. Castro, Theo A. Knijnenberg, Mauro A.A. Castro, Vinicius S. Chagas, Victor H. Apolonio, Verena Friedl, Joshua M. Stuart, Vladislav Uzunangelov, Christopher K. Wong, Rameen Beroukhim, Andrew D. Cherniack, Galen F. Gao, Gad Getz, Stephanie H. Hoyt, Xavier Loinaz, Whijae Roh, Chip Stewart, Lindsay Westlake, Christopher C. Benz, Jasleen K. Grewal, Steven J.M. Jones, A. Gordon Robertson, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Anab Kemal, Roy Tarnuzzer, Peggy I. Wang, Zhining Wang, Liming Yang, Jean C. Zenklusen, Rehan Akbani, Bradley M. Broom, Zhenlin Ju, Andre Schultz, Akinyemi I. Ojesina, Katherine A. Hoadley, Avantika Lal, Daniele Ramazzotti, Chen Wang, Alexander J. Lazar, Lewis R. Roberts, Bahar Tercan, Taek-Kyun Kim, Ilya Shmulevich, Paulos Charonyktakis, Vincenzo Lagani, Ioannis Tsamardinos, Esther Drill, Ronglai Shen, Martin L. Ferguson, Kami E. Chiotti, Kyle Ellrott, Brian J. Karlberg, Jordan A. Lee, Eve Lowenstein, Paul T. Spellman, Adam Struck, Christina Yau, D. Neil Hayes, Toshinori Hinoue, Hui Shen, Peter W. Laird   +78 more
doaj   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Protocol to recover single-cell gene expression profiles from spatial transcriptomics data using cluster computing

STAR Protocols
Summary: Many widely used spatial transcriptomics technologies, such as Visium, capture data at multicellular resolution, precluding single-cell analysis.
Young Je Lee, Hao Chen, Jose Lugo-Martinez   +2 more
doaj   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Protocol for functional screening of CFTR-targeted genetic therapies in patient-derived organoids using DETECTOR deep-learning-based analysis

STAR Protocols
Summary: Here, we present a protocol for the rapid functional screening of gene editing and addition strategies in patient-derived organoids using the deep-learning-based tool DETECTOR (detection of targeted editing of cystic fibrosis transmembrane ...
Mattijs Bulcaen, Ronald B. Liu, Kasper Gryspeert, Sam Thierie, Anabela S. Ramalho, François Vermeulen, Xavier Casadevall I Solvas, Marianne S. Carlon   +7 more
doaj   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Using the e-learning course “Analytic Geometry” in the process of training students majoring in Computer Science and Information Technology

CTE Workshop Proceedings, 2019
As a result of literature analysis the expediency of free access of bachelors majoring in Computer Sciences and Information Technologies to modern information educational resources, in particular, e-learning courses in the process of studying ...
Oksana M. Hlushak, Volodymyr V. Proshkin, Oksana S. Lytvyn   +2 more
doaj   +1 more source

Facilitating academic words learning: a data-driven approach using a collocation consultation system built from open access research papers [PDF]

, 2018
It is essential and beneficial for ESP students to master collocations of a set of core academic words. Corpus analysis tools (e.g. concordancers) have been widely used in facilitating collocation learning, and promising results have been demonstrated in
Yu, Alex
core  

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source