Results 91 to 100 of about 2,508,631 (310)

Scheduling Algorithms for a Hybrid Flow Shop under Uncertainty

open access: yesAlgorithms, 2020
In modern production systems, scheduling problems have to be solved in consideration of frequently changing demands and varying production parameters.
Christin Schumacher, Peter Buchholz
doaj   +1 more source

Computer-Simulation Model Theory (P= NP is not provable) [PDF]

open access: yesarXiv, 2019
The simulation hypothesis says that all the materials and events in the reality (including the universe, our body, our thinking, walking and etc) are computations, and the reality is a computer simulation program like a video game. All works we do (talking, reasoning, seeing and etc) are computations performed by the universe-computer which runs the ...
arxiv  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Phase diagram of silica from computer simulation

open access: yes, 2004
We evaluate the phase diagram of the ``BKS'' potential [Van Beest, Kramer and van Santen, Phys. Rev. Lett. 64, 1955 (1990)], a model of silica widely used in molecular dynamics (MD) simulations. We conduct MD simulations of the liquid, and three crystals
Francesco Sciortino   +6 more
core   +1 more source

CloudSim Express: A Novel Framework for Rapid Low Code Simulation of Cloud Computing Environments [PDF]

open access: yesarXiv, 2023
Cloud computing environment simulators enable cost-effective experimentation of novel infrastructure designs and management approaches by avoiding significant costs incurred from repetitive deployments in real Cloud platforms. However, widely used Cloud environment simulators compromise on usability due to complexities in design and configuration ...
arxiv  

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

open access: yesFEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya   +3 more
wiley   +1 more source

Biotite: new tools for a versatile Python bioinformatics library

open access: yesBMC Bioinformatics, 2023
Background Biotite is a program library for sequence and structural bioinformatics written for the Python programming language. It implements widely used computational methods into a consistent and accessible package.
Patrick Kunzmann   +7 more
doaj   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

When medical trainees encountering a performance difficulty: evidence from pupillary responses

open access: yesBMC Medical Education, 2022
Background Medical trainees are required to learn many procedures following instructions to improve their skills. This study aims to investigate the pupillary response of trainees when they encounter moment of performance difficulty (MPD) during skill ...
Xin Liu   +5 more
doaj   +1 more source

One-Way Quantum Computer Simulation [PDF]

open access: yesInternational Journal of Microprocessors and Microsystems, Elsevier, Vol. 39, No. 3, pp. 210-222, May 2015, 2015
In one-way quantum computation (1WQC) model, universal quantum computations are performed using measurements to designated qubits in a highly entangled state. The choices of bases for these measurements as well as the structure of the entanglements specify a quantum algorithm.
arxiv  

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