Results 101 to 110 of about 3,380,527 (288)

ACCOUNTING FOR COMPUTER SOFTWARE COSTS [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
Hundreds of thousands of companies all over the world use computers, with different software products and other useful applications. Nowadays, businesses need these modern tools.
TEIUŞAN SORIN-CIPRIAN
doaj  

A steel defect detection method based on edge feature extraction via the Sobel operator

Scientific Reports
Scratches and cracks in steel severely affect its service life and performance. However, owing to the irregular shapes and sizes of steel surface defects, defects within the same class may be different, whereas defects between classes may be similar ...
Yuanyuan Wang, Tongtong Yin, Xiuchuan Chen, Abdullahi Suleiman Hauwa, Boyang Deng, Yemeng Zhu, Shangbing Gao, Haiyan Zang, Hu Zhao   +8 more
doaj   +1 more source

A methodology for unified hardware-software design [PDF]

Unified hardware-software design for digital ...
Chu, Y., Pardo, O. R., Yeh, J.
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

A novel image encryption scheme using 3D chaotic maps with Josephus permutation and dynamic diffusion

Journal of King Saud University: Computer and Information Sciences
With the rapid development of digital communication, cloud computing, and intelligent applications such as smart healthcare and the Internet of Things (IoT), secure image transmission has become a critical challenge.
Wanru Lu, Chunhua Jin, Jiahao Wang, Xinying Liu, Junyi Liu, Zhonghao Zhai   +5 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Node classification in complex networks based on multi-view debiased contrastive learning

Complex & Intelligent Systems
In complex networks, contrastive learning has emerged as a crucial technique for acquiring discriminative representations from graph data. Maximizing the similarity among relevant sample pairs while minimizing that among irrelevant pairs is pivotal in ...
Zhe Li, Lei Zhou, Yandong Hou, Min Ji, Zhuanzheng Hang, Bolun Chen   +5 more
doaj   +1 more source

The software patent experiment. [PDF]

Over the past two decades, the scope of technologies that can be patented has been expanded to include many items previously thought unsuitable for patenting, for example, computer software. Today, the U.S.
James Bessen, Robert Hunt
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Analyzing the 2021 Kaseya Ransomware Attack: Combined Spearphishing Through SonicWall SSLVPN Vulnerability

IET Information Security
In July 2021, the IT management software company Kaseya was the victim of a ransomware cyberattack. The perpetrator of this attack was ransomware evil (REvil), an allegedly Russian-based ransomware threat group. This paper addresses the general events of
Suman Bhunia, Matthew Blackert, Henry Deal, Andrew DePero, Amar Patra   +4 more
doaj   +1 more source