Results 81 to 90 of about 6,275,059 (295)

Usability and open-source software development [PDF]

open access: yes, 2001
Open-source is becoming an increasingly popular software development method. This paper reports a usability study of the open-source Greenstone Digital Library collection-building software.
Stuart A. Yeates   +5 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Computing and software

open access: yesAnimal Biodiversity and Conservation, 2004
The reality is that the statistical methods used for analysis of data depend upon the availability of software. Analysis of marked animal data is no different than the rest of the statistical field. The methods used for analysis are those that are available in reliable software packages.
White, G. C., Hines, J. E.
openaire   +5 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Software Portability for Computer Algebra

open access: yes
We have been involved in the creation of multiple software systems for computer algebra, including Reduce, Maple, Axiom and Aldor as well as a number of smaller specialised programs. We relate observations on how the meaning of software portability has changed over time and how it continues to evolve.
Arthur C. Norman, Stephen M. Watt
openaire   +4 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Requirements engineering: a close look at industry needs and a model curricula [PDF]

open access: yes, 2004
Research endeavours in software development have found that failures and deficiencies of software systems are often rooted in the requirements activities undertaken.
Oliver Minor   +5 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Teaching Software Verification and Validation Course: a Case Study

open access: yes, 2014
Ozcelik, Erol/0000-0003-0370-8517; Cagiltay, Nergiz/0000-0003-0875-9276; Sengul, Gokhan/0000-0003-2273-4411Mishra, Alok/0000-0003-1275-2050; Mishra, Deepti/0000-0001-5144-3811Software verification and validation (V & V) is one of the significant areas of
Hacaloglu, Tuna   +2 more
core   +1 more source

A verifiable secure aggregation for federated learning with low-quality data

open access: yesJournal of King Saud University: Computer and Information Sciences
Federated learning (FL) enables multiple users to collaboratively train a shared model while keeping their raw data locally stored, and it has demonstrated significant potential across various domains.
Jie Zhou   +4 more
doaj   +1 more source

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