Results 51 to 60 of about 3,380,527 (288)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Vehicle detection in drone aerial views based on lightweight OSD-YOLOv10
Scientific ReportsTo address the challenges of low performance in vehicle image detection from UAV aerial imagery, difficulties in small target feature extraction, and the large parameter size of existing models, we propose the OSD-YOLOv10 algorithm, an enhanced version ...
Yang Zhang +6 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Justification of the costs of forest reclamation of lands subject to desertification
Siberian Journal of Life Sciences and AgricultureBackground. In recent decades, environmental problems related to land degradation and depletion of soil cover have become especially acute in the south of Russia. The consequences of these threats are commonly referred to as desertification.
Evgenia A. Korneeva
doaj +1 more source
Motivation, Design, and Ubiquity: A Discussion of Research Ethics and Computer Science
, 2006 Modern society is permeated with computers, and the software that controls them can have latent, long-term, and immediate effects that reach far beyond the actual users of these systems.
Wright, David R.
core +1 more source
, 2009 This article seeks to explore new digital ways of distinguishing between scribal hands in medieval manuscripts. An analysis of traditional palaeographical approaches to hand identification will be followed by a discussion in which attention will be paid ...
Aussems, Mark, Brink, Axel
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Robin Hood às avessas: software, pirataria e direito autoral
Revista Direito GVResumo Como a pirataria influencia o mercado de programas de computador? A presente pesquisa visa analisar os efeitos respectivos da pirataria tanto para as grandes corporações quanto para os pequenos desenvolvedores de software.
Marcos Vinício Chein Feres +2 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Non-developmental item computer systems and the malicious software threat [PDF]
The following subject areas are covered: a DOD development system - the Army Secure Operating System; non-development commercial computer systems; security, integrity, and assurance of service (SI and A); post delivery SI and A and malicious software ...
Bown, Rodney L.
core +1 more source