Results 121 to 130 of about 1,778,148 (300)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Using Electronic Systems for Document Management in Economic Entities [PDF]

open access: yes
Document workflow and management, be them scanned documents, computer-generated e-documents or complex file formats, are critical elements for the success of an organization.
Anca MEHEDINTU   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

ENSURING THE QUALITY OF ENGINEERING TRAINING FOR THE AUTOMOBILE AND ROAD-CONSTRUCTION COMPLEX OF RUSSIA

open access: yesВысшее образование в России, 2016
The article focuses on the organization at MADI of competency-based education system with modular learning process. The transition to two-tier education system entails the introduction of education programs of a new generation, the improvement of ...
Viktor V. Ushakov
doaj  

SPAR data handling utilities [PDF]

open access: yes
The SPAR computer software system is a collection of processors that perform particular steps in the finite-element structural analysis procedure. The data generated by each processor are stored on a data base complex residing on an auxiliary storage ...
Giles, G. L., Haftka, R. T.
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Research on optimization of air flow organization in substation room air conditioning based on CFD

open access: yesDianxin kexue
Due to the continuous improvement of the computer network communication level and the acceleration of data transmission speed, the hardware configuration of the digital signal processing room on the second floor of this unit has become more intensive ...
Can CHEN   +5 more
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

MOBILITY AS A COMPONENT OF PERSPECTIVE OF MODERN EDUCATIONAL PROCESS

open access: yesІнформаційні технології і засоби навчання, 2014
This article is devoted to the prospects of new approaches to training and retraining system of postgraduate education from the perspective of the concept of «mobility», which is due to the dynamic development of the modern world, information and ...
Larysa L. Familiarska
doaj  

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