Results 141 to 150 of about 228,687 (264)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

DermIDS: Dermatology imaging data structure for scalable and interoperable AI systems. [PDF]

Proc SPIE Int Soc Opt Eng
Cho C, McNeil AJ, Jiang B, Saunders AM, Rudravaram G, Liu Y, Moyer D, Dawant BM, Landman BA, Tkaczyk ER.   +9 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Decoding the OR Black Box and Similar Technologies and Considerations in Otolaryngologic Surgery. [PDF]

Laryngoscope Investig Otolaryngol
Li SC, Bain A, Tan D, Ji H.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Systemic testosterone induces structural, immunological, and sex steroid receptor changes in human XX skin. [PDF]

Sci Rep
Dabrosin N, Abrahamsson A, Kratz G.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Feasibility and Safety of a Computer-Controlled Device for Transradial Cerebral Angiography: A Prospective Pilot Study. [PDF]

J Neuroendovasc Ther
Tanaka S, Hirata K, Uramaru K, Matsumura H, Yoshimoto T, Hosoo H, Ito Y, Hayakawa M, Marushima A, Yamagami H, Matsumaru Y.   +10 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Health Professionals' Readiness and Its Associated Factors to Implement Telemedicine System at Public Hospitals in Harari Region, Eastern Ethiopia, 2024: A Cross-Sectional Study. [PDF]

Health Sci Rep
Hailu S, Negash B, Kassaye D, Ahmed N, Yeshitila M, Mezmur H.   +5 more
europepmc   +1 more source