Results 61 to 70 of about 32,367 (309)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

From linear questionnaires to computer-adaptive tests: Content development and calibration of the Digital Eye Strain Computer Adaptive Test (DESCAT) [PDF]

open access: yes, 2022
We published in 2015 a linear Rasch-based scale (Computer Vision Symptom Scale, aka CVSS17) for measuring the computer-related visual and ocular symptoms in workers using video-display terminals.
Barrio De Santos, Ana Rosa   +3 more
core  

Prediction of Computer Vision Syndrome in Health Personnel by Means of Genetic Algorithms and Binary Regression Trees

open access: yesSensors, 2019
One of the major consequences of the digital revolution has been the increase in the use of electronic devices in health services. Despite their remarkable advantages, though, the use of computers and other visual display terminals for a prolonged time ...
Eva María Artime Ríos   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Usability of digital libraries: a study based on the areas of information Science and Human-Computer Interaction [PDF]

open access: yes, 2005
The conception, planning and implementation of digital libraries, in any area of knowledge, demand innumerable studies in order to verify and guarantee their adequacy to the users’ necessities. Such studies find methodological, conceptual and theoretical
Ferreira, Sueli Mara   +1 more
core  

Conformal mapping for multiple terminals [PDF]

open access: yes, 2016
: Conformal mapping is an important mathematical tool that can be used to solve various physical and engineering problems in many fields, including electrostatics, fluid mechanics, classical mechanics, and transformation optics.

core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Access to the energy system network simulator (ESNS), via remote computer terminals. [BNL CDC 7600/6600 computer facility] [PDF]

open access: yes, 1976
The Energy System Network Simulator (ESNS) flow model is installed on the Brookhaven National Laboratory (BNL) CDC 7600/6600 computer facility for access by off-site users.
Reisman, A W
core   +1 more source

Computer Vision Syndrome Prevalence and Associated Factors Among the Medical Student in Kist Medical College

open access: yesNepalese Medical Journal, 2018
Correction: In the publication, the study period was missed. The study period "from 2nd April 2018 to 15th April 2018" has been added. Introduction: Computers and other visual display terminals are now an essential part of our daily life.
Anjila Basnet   +3 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

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