Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Local Descriptors Optimized for Average Precision
Extraction of local feature descriptors is a vital stage in the solution pipelines for numerous computer vision tasks. Learning-based approaches improve performance in certain tasks, but still cannot replace handcrafted features in general. In this paper,
He, Kun, Lu, Yan, Sclaroff, Stan
core +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Segmentation of Oil Spills on Side-Looking Airborne Radar Imagery with Autoencoders
In this work, we use deep neural autoencoders to segment oil spills from Side-Looking Airborne Radar (SLAR) imagery. Synthetic Aperture Radar (SAR) has been much exploited for ocean surface monitoring, especially for oil pollution detection, but few ...
Antonio-Javier Gallego +3 more
doaj +1 more source
The Incremental Multiresolution Matrix Factorization Algorithm
Multiresolution analysis and matrix factorization are foundational tools in computer vision. In this work, we study the interface between these two distinct topics and obtain techniques to uncover hierarchical block structure in symmetric matrices -- an ...
Ithapu, Vamsi K. +3 more
core +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Anomaly Detection in Natural Scene Images Based on Enhanced Fine-Grained Saliency and Fuzzy Logic
This paper proposes a simple yet effective method for anomaly detection in natural scene images improving natural scene text detection and recognition.
Hamam Mokayed +5 more
doaj +1 more source
Efficient Regularization of Squared Curvature [PDF]
Curvature has received increased attention as an important alternative to length based regularization in computer vision. In contrast to length, it preserves elongated structures and fine details.
Boykov, Yuri +4 more
core
Stopping Criterion for the Mean Shift Iterative Algorithm
Image segmentation is a critical step in computer vision tasks constituting an essential issue for pattern recognition and visual interpretation. In this paper, we propose a new stopping criterion for the mean shift iterative algorithm by using images ...
Pereira, Osvaldo +4 more
core +1 more source

