Results 61 to 70 of about 554,243 (265)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock, Jin Nakahara, Becky Parks, Kerstin Allen, Sami Fam   +4 more
wiley   +1 more source

Benchmarking deep learning models for predicting anticancer drug potency (IC50) with insights for medicinal chemists

Communications Chemistry
Potency (IC50) prediction of small molecules is pivotal for anticancer drug development. This study benchmarked five deep learning (DL) models for IC50 prediction—DeepCDR, DrugCell, PaccMann, Precily, and tCNN—against a simple mean-based Baseline using ...
Udbhas Garai, Aditya S. Pal, Koyel Ghosh, Deepak B. Salunke, Utpal Garain   +4 more
doaj   +1 more source

What Will I Do Next? The Intention from Motion Experiment

, 2017
In computer vision, video-based approaches have been widely explored for the early classification and the prediction of actions or activities. However, it remains unclear whether this modality (as compared to 3D kinematics) can still be reliable for the ...
Becchio, Cristina, Cavallo, Andrea, Cavazza, Jacopo, Koul, Atesh, Murino, Vittorio, Zunino, Andrea   +5 more
core   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

A deep learning framework for species-level identification of root-knot nematodes using perineal pattern images

Scientific Reports
The use of machine learning is an emerging approach in precision agriculture, including pest identification, disease diagnostics, and soil health monitoring.
Sristi Das, Koyel Ghosh, Sandip Mondal, Suvasri Dutta, Matiyar Rahaman Khan, Utpal Garain, Abhishek Mukherjee   +6 more
doaj   +1 more source

Hierarchical local global transformer for point clouds analysis

International Journal of Applied Earth Observations and Geoinformation
Transformer networks have demonstrated remarkable performance in point cloud analysis. However, achieving a balance between local regional context and global long-range context learning remains a significant challenge.
Dilong Li, Shenghong Zheng, Ziyi Chen, Xiang Li, Lanying Wang, Jixiang Du   +5 more
doaj   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

PointSSM: State space model for large-scale LiDAR point cloud semantic segmentation

International Journal of Applied Earth Observations and Geoinformation
LiDAR point cloud semantic segmentation is the foundation of numerous practical applications. Recently, the Mamba, as a promising alternative to Transformer, has been getting intense attention in this field.
Dilong Li, Jianlong Guan, Ziyi Chen, Jingchen Liao, Jixiang Du   +4 more
doaj   +1 more source

Simultaneous Facial Landmark Detection, Pose and Deformation Estimation under Facial Occlusion

, 2017
Facial landmark detection, head pose estimation, and facial deformation analysis are typical facial behavior analysis tasks in computer vision. The existing methods usually perform each task independently and sequentially, ignoring their interactions. To
Gou, Chao, Ji, Qiang, Wu, Yue
core   +1 more source