Results 201 to 210 of about 132,587 (305)

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Computerised Algorithms Showed Promise in Identifying Swedish Children With Atypical Growth Patterns. [PDF]

Acta Paediatr
Gelander L, Niklasson A, Holmgren A, Pivodic A, Saari A, Sankilampi U, Dunkel L, Albertsson-Wikland K.   +7 more
europepmc   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

Assessment of validity, reliability, responsiveness and acceptability of seven Dutch-Flemish PROMIS computerised adaptive tests (CATs) in Dutch people with type 2 diabetes: an observational and qualitative study. [PDF]

BMJ Open
Groeneveld L, Terwee CB, van der Willik EM, van Ittersum FJ, Langendoen-Gort M, Pals F, Blom MT, Beulens JWJ, Elders PJM, Rutters F.   +9 more
europepmc   +1 more source

Laser‐Assisted Processing and Modification of Bioactive Glasses: A Review

Advanced Healthcare Materials, EarlyView.
Laser technologies provide powerful tools to process and transform bioactive glasses for advanced biomedical applications. This review discusses laser‐matter interaction mechanisms, laser surface engineering, and laser‐assisted fabrication of scaffolds and nanofibers.
Antonio Riveiro, Mario González‐Quintas, Mónica Fernández‐Arias, Jesús del Val, Félix Quintero, Rafael Comesaña, Fernando Lusquiños, Julian R. Jones, Juan Pou   +8 more
wiley   +1 more source

Illicit trafficking in nuclear materials and radioactive substances. Implementation of the guidelines laid down in the communication from Commission of 7 September 1994 (COM (94) 383) and in the conclusion of the Essen European Council. Communication from the Commission to the Council and the European Parliament. COM (96) 171 final, 19 April 1996 [PDF]

, 1996

core  

Understanding the Effects of Conductive Polymer Electrode Coating on Recorded Neural Signals

Advanced Healthcare Materials, EarlyView.
Conductive polymer coatings are widely explored to improve the quality of signals recorded with chronically implanted neural electrodes, offering enhanced biocompatibility along with reduced electrode impedance. Combining computational modelling and data from PEDOT:PTS coated and PtIr electrodes in rats, we show that improvements in signal quality with
Karthik Sridhar, Judith Evers, Alexandre Trotier, Manus Biggs, Madeleine M. Lowery   +4 more
wiley   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

The computerised PROTECT Cognitive Test System is sensitive to dementia and correlates with Alzheimer-related blood biomarkers

Corbett A, Palmer A, Sander M, Davis C, Stych K, O’Leary M, Huntley J, Aarsland D, Castellanos-Perilla N, Botero-Rodriguez F, Griffioen G, Nuytten M, Ashton N, Huber H, Hampshire A, Ballard C.   +15 more
europepmc   +1 more source

Intra-individual variability in cognitive performance predicts falls in older adults with chronic stroke. [PDF]

Aging Clin Exp Res
Dimri V, Davis JC, Boa Sorte Silva NC, Balbim GM, Eng JJ, Liu-Ambrose T.   +5 more
europepmc   +1 more source