Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum +5 more
wiley +1 more source
The SAVE FGR study: Short term variation Analysis versus Visual Evaluation of cardiotocography in early-onset Fetal Growth Restriction to trigger expedited birth - study protocol for a stepped wedge cluster randomized trial. [PDF]
Bruins ME +12 more
europepmc +1 more source
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
Clinical Effectiveness of Treatments for Mild Cognitive Impairment in Adults: A Systematic Review. [PDF]
Cepeda-Pineda D +9 more
europepmc +1 more source
A vision of Britain through time: making long-run statistics of inequality accessible to all [PDF]
Southall, Humphrey
core
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang +13 more
wiley +1 more source
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery +10 more
wiley +1 more source
"Ultrasound innovations in diaphragm assessment: an integrative review of expanding clinical applications." I. Neto Silva, C. Bennett, J.A. Duarte and K. Bendjelid. <i>Eur Respir Rev</i> 2025; 34: 250089. [PDF]
europepmc +1 more source
Contrasting attitudes towards current and future artificial intelligence applications for computerised interpretation of electrocardiograms: a clinical stakeholder interview study. [PDF]
Hughes-Noehrer L +5 more
europepmc +1 more source

