Results 41 to 50 of about 885,420 (337)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Cognitive Rehabilitation in Schizophrenia-Associated Cognitive Impairment: A Review

Neurology International, 2022
Patients suffering from schizophrenia often experience cognitive disturbances. Cognitive rehabilitation—computerized or non-computerized—is widely known as an alternative way to enhance cognitive functioning in patients with schizophrenia. The aim of the
Elli Zoupa, Olympia Bogiatzidou, Vasileios Siokas, Ioannis Liampas, Georgios Tzeferakos, Venetsanos Mavreas, Stelios Stylianidis, Efthimios Dardiotis   +7 more
doaj   +1 more source

Welding skate with computerized control Patent [PDF]

, 1969
Development of apparatus for automatically changing carriage speed of welding machine to obtain constant speed of torch along work ...
Wall, W. A., Jr.
core   +1 more source

Expertise and the interpretation of computerized physiological data: implications for the design of computerized monitoring in neonatal intensive care [PDF]

, 2001
This paper presents the outcomes from a cognitive engineering project addressing the design problems of computerized monitoring in neonatal intensive care.
ALBERDI, ALBERDI, ALBERDI, ANDY LYON, AZEVEDO, BARNARD, BOSHUIZEN, CARD, CARROLL, CHASE, CHI, CLAESSEN, COIERA, COIERA, COIERA, CUNNINGHAM, CUNNINGHAM, DEERE, EDWORTHY, EGAN, ELSTEIN, ELSTEIN, ERICSSON, ERICSSON, ERICSSON, ERICSSON, EUGENIO ALBERDI, FELTOVICH, FELTOVICH, GILHOOLY, GILHOOLY, GRAY, GREEN, GREEN, GREMY, HAIMOWITZ, JAN REISS, JIM HUNTER, JOSEPH, JULIE-CLARE BECHER, KEN GILHOOLY, LANDAUER, LARKIN, LARKIN, LEMIEUX, LESGOLD, LESGOLD, LOGIE, LONG, LONG, MCINTOSH, MORGAN, NEIL MCINTOSH, NENOV, NORMAN, PATEL, PATEL, PATEL, PATEL, PATEL, ROBERT LOGIE, SALATIAN, SCHMIDT, SCHMIDT, TABOADA, WICKENS   +65 more
core   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Assessment of soft and hard tissue characteristics of ridge preservation at molar extraction sites with severe periodontitis: a randomized controlled trial

BMC Oral Health, 2022
Background Changes in alveolar bone dimension after tooth extraction may affect placement of the subsequent implant, resulting in ridge deficiency that can adversely impact long-term implant stability or aesthetics.
Haoyun Zhang, Yiping Wei, Tao Xu, Min Zhen, Cui Wang, Ziyao Han, Wenjie Hu, Kwok-Hung Chung   +7 more
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Improvement of upsetting process of four-beam workpieces based on computerized and physical modeling [PDF]

FME Transactions, 2020
The method of upsetting of large ingots has been investigated in this work. The proposed method consists in upsetting of profiled workpieces with concave faces. An angle of the concave faces was 150°. A relative depth of the concave faces has been varied
Markov Oleg E., Kukhar Volodymyr V., Zlygoriev Vitalii N., Shapoval Alexander A., Khvashchynskyi Anton S., Zhytnikov Roman U.   +5 more
doaj  

Video information system [PDF]

, 1972
Computerized information storage and display system directs storage of documents, drawings, photographs, fingerprints, etc., and permits rapid retrieval for real-time viewing on remote ...
Ritch, E. R.
core   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source