Results 101 to 110 of about 4,518,457 (289)

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Managing ADHD Symptoms in Children Through the Use of Various Technology-Driven Serious Games: A Systematic Review

open access: yesMultimodal Technologies and Interaction
Children with attention deficit hyperactivity disorder (ADHD) frequently experience impairments in a range of abilities. Due to their poor attention and concentration, they find it challenging to stay focused when learning.
Aikaterini Doulou   +3 more
doaj   +1 more source

Disponibilidad léxica y anglicismos informáticos en los centros de interés: Internet, software y hardware.

open access: yesOdisea, 2017
Resumen: Este trabajo recoge los resultados de un estudio sobre la disponibilidad léxica de los estudiantes de traducción de la Universidad de Las Palmas de Gran Canaria (España) en torno a tres centros de interés del ámbito de la informática: Internet ...
Carmen Isabel Luján García   +1 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Computers for Lattice Field Theories

open access: yes, 1994
Parallel computers dedicated to lattice field theories are reviewed with emphasis on the three recent projects, the Teraflops project in the US, the CP-PACS project in Japan and the 0.5-Teraflops project in the US.
Iwasaki, Y.
core   +1 more source

Comparison of Perceived Musculoskeletal Discomfort Among Six Common Postures for Laptop Use in Female Students

open access: yesPhysical Treatments, 2018
Purpose: The present study aimed to compare Musculoskeletal Discomforts (MSDs) among six different common postures while working with laptop in female students of University of Tehran, Tehran City, Iran.
Nahid Allafan   +4 more
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Computação em química teórica: informações técnicas Computation in theoretical chemistry: technical informations

open access: yesQuímica Nova, 2001
The purpose of this work is to demonstrate the usefulness of low cost high performance computers. It is presented technics and software packages used by computational chemists.
Nelson Henrique Morgon
doaj   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

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