Results 91 to 100 of about 1,105,055 (318)

Computability theory

, 2011
Short introduction to computability theory and computational complexity.
openaire   +1 more source

High-Performance Computing: An Agenda for the Social Sciences and the Humanities in Canada

Digital Studies, 2009
None
John Bonnett
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Training and Serving System of Foundation Models: A Comprehensive Survey

IEEE Open Journal of the Computer Society
Foundation models (e.g., ChatGPT, DALL-E, PengCheng Mind, PanGu-$\Sigma$) have demonstrated extraordinary performance in key technological areas, such as natural language processing and visual recognition, and have become the mainstream trend of ...
Jiahang Zhou, Yanyu Chen, Zicong Hong, Wuhui Chen, Yue Yu, Tao Zhang, Hui Wang, Chuanfu Zhang, Zibin Zheng   +8 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Computational Creativity Without Computers

Journal of Science and Technology of the Arts
Generative artificial intelligence algorithms and applications pose new challenges to the creativity of artists and educators. This study delves into the aesthetic and methodological contradictions of computational creativity, where issues arise from the clash between Romantic aesthetics and the lack of a proper connection between digital and ...
Roncoroni, Umberto, Bailón, Jaime E.
openaire   +4 more sources

On Computability of Computable Problems

, 2023
12 Pages,4 figures, and 1 ...
openaire   +2 more sources

A method for obtaining the characteristic equation of a matrix and computing the associated modal columns [PDF]

, 1950
Henry E. Fettis
openalex   +1 more source