Results 111 to 120 of about 2,356,177 (297)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 1979 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +2 more sources
Computing News ; vol. 19, no. 04 (Fall 2004)
, 2003 24 p.Get Your Free Duckware and Windows Security CDs -- Manage Your UO Computing Account Online -- What You Need to Know About the 2004 Windows Security CD -- How to Begin Using Your UO Computing Account -- Map of Wireless Coverage on Campus ...
Winslow, Joyce +1 more
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Computers and Computing in Society [PDF]
NTM Zeitschrift für Geschichte der Wissenschaften, Technik und Medizin, 2020 openaire +2 more sources
An apparently innocent problem in Membrane Computing [PDF]
, 2019 The search for effcient solutions of computationally hard problems by means of families of membrane systems has lead to a wide and prosperous eld of research.
Orellana Martín, David +4 more
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Computing News ; vol. 14, no. 01 (Fall 1998)
, 1998 20 p.How to Change Your Password -- Access Your Account Information with DuckWeb -- 1998 Duckware CD-Rom Available -- 'Survival Skills' Workshops -- Computing Center Who's Who -- V.90 Comes to Campus -- Web Server Software Upgrade -- Web Proxy Server ...
Winslow, Joyce +1 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source