Results 121 to 130 of about 1,996,524 (318)

Cloud Computing: Exploring the scope [PDF]

open access: yes, 2010
Cloud computing refers to a paradigm shift to overall IT solutions while raising the accessibility, scalability and effectiveness through its enabling technologies.
Maurya, Brajesh Kumar
core  

Optical Computing and Computational Complexity

open access: yes, 2006
This work concerns the computational complexity of a model of computation that is inspired by optical computers. The model is called the continuous space machine and operates in discrete timesteps over a number of two-dimensional images of fixed size and arbitrary spatial resolution.
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Search Based Software Engineering in Membrane Computing [PDF]

open access: yes, 2019
This paper presents a testing approach for kernel P Systems (kP systems), based on test data generation for a given scenario. This method uses Genetic Algorithms to generate the input sets needed to trigger the given computation ...
Gheorghe, Marian   +3 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

FASCS: A Family Approach for Developing Scientific Computing Software [PDF]

open access: yes, 2011
Scientific Computing (SC) software has had considerable success in achieving improvements in the quality factors of accuracy, precision and efficiency.
Yu, Wen
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Comparison of gender relation to information and communication technologies at the to BERG Faculty [PDF]

open access: yesActa Montanistica Slovaca, 2005
The contribution deals with the valuation of computer literacy poll and students‘ readiness to ICT (Information and Communication Technologies) at the beginning of the academic study. The questionnaire was realized in the electronic form and was oriented
Pavel Horovčák
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Computing News ; vol. 08, no. 03 (January 1993) [PDF]

open access: yes, 1993
4 p.Meet Jacqueline Granier, Gopher Pioneer -- WHAT'S NEW?? -- MPP Updates -- Something's Changed. . . -- Computing News Takes New Tack -- System 7 . 1 Now on AppleShare -- Winter Workshop Schedule -- Microcomputer Workshops -- BRUCE Automates Account ...
Winslow, Joyce   +1 more
core  

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