Results 111 to 120 of about 4,892,723 (368)

Computable structures on topological manifolds [PDF]

open access: yesarXiv, 2017
We propose a definition of computable manifold by introducing computability as a structure that we impose to a given topological manifold, just in the same way as differentiability or piecewise linearity are defined for smooth and PL manifolds respectively.
arxiv  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Computing with Functionals—Computability Theory or Computer Science?

open access: yesBulletin of Symbolic Logic, 2006
AbstractWe review some of the history of the computability theory of functionals of higher types, and we will demonstrate how contributions from logic and theoretical computer science have shaped this still active subject.
openaire   +3 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Computational models for parallel computers [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series A, Mathematical and Physical Sciences, 1988
Computational models define the usage patterns of a computer. They can be used to derive the architecture of the machine, provide guidelines for programming tools, and suggest how the machine should be used in applications. Identifying computational models is especially important for parallel computers, because their architectures and usages are still ...
openaire   +2 more sources

The Mode of Computing

open access: yes, 2019
The Turing Machine is the paradigmatic case of computing machines, but there are others, such as Artificial Neural Networks, Table Computing, Relational-Indeterminate Computing and diverse forms of analogical computing, each of which based on a ...
Pineda, Luis A.
core  

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Computer animation

open access: yesACM Computing Surveys, 1985
Computer animation may be defined as a technique in which the illusion of movement is created by displaying on a screen or recording on a device a series of individual states of a dynamic scene. The key issue of computer animation is defining motion, commonly known as motion control methods (MCMs).
Magnenat Thalmann, N, Thalmann, D
openaire   +5 more sources

Real-number Computability from the Perspective of Computer Assisted Proofs in Analysis [PDF]

open access: yesarXiv, 2017
Inspired by computer assisted proofs in analysis, we present an interval approach to real-number computations.
arxiv  

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

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