Results 151 to 160 of about 4,697,585 (340)
Energy Minimization for Mobile Edge Computing Networks with Time-Sensitive Constraints [PDF]
, 2020 Junjie Yu +6 more
openalex +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Other Titles from ISTE in Information Systems, Web and Pervasive Computing [PDF]
, 2014 openalex +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
ON NUMERICAL PROCEDURES COMPUTING STATICAL RESPONSE OF GEOMETRICALLY NONLINEAR DISCRETE SYSTEMS
, 1982 Masahiro Ai, Fumio Nishino
openalex +2 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Stories Matter: Conceptual Challenges in the Development of Oral History Database Building Software
Forum: Qualitative Social Research, 2010 Stories Matter is new oral history database building software designed by an interdisciplinary team of oral historians and a software engineer affiliated with the Centre for Oral History and Digital Storytelling at Concordia University in Montreal ...
Erin Jessee +2 more
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