Results 51 to 60 of about 180,409 (146)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

A Comprehensive Review of EEG-Based Seizure Detection Techniques

open access: yesIEEE Access
The automated classification and prediction of epileptic seizures using electroencephalography (EEG) remains a dynamic and critical area of interdisciplinary research, situated at the intersection of neuroscience and computational intelligence.
Goldwyn Sudhakar Jebaraj   +1 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

On-line Handwritten Character Recognition: An Implementation of Counterpropagation Neural Net [PDF]

open access: yes, 2005
On-line handwritten scripts are usually dealt with pen tip traces from pen-down to pen-up positions. Time evaluation of the pen coordinates is also considered along with trajectory information.
Mohamad, Dzulkifli   +2 more
core  

Classification of Large-Scale Fundus Image Data Sets: A Cloud-Computing Framework

open access: yes, 2016
Large medical image data sets with high dimensionality require substantial amount of computation time for data creation and data processing. This paper presents a novel generalized method that finds optimal image-based feature sets that reduce ...
Roychowdhury, Sohini
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Advanced applications in chronic disease monitoring using IoT mobile sensing device data, machine learning algorithms and frame theory: a systematic review

open access: yesFrontiers in Public Health
The escalating demand for chronic disease management has presented substantial challenges to traditional methods. However, the emergence of Internet of Things (IoT) and artificial intelligence (AI) technologies offers a potential resolution by ...
Yu Liu, Boyuan Wang, Boyuan Wang
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Best practices for AI-based image analysis applications in aquatic sciences: The iMagine case study

open access: yesEcological Informatics
The iMagine project is an EU-funded initiative led by the EGI Foundation. One of the objectives of this project is to provide an AI platform that leverages AI-powered tools to improve the processing and analysis of imaging data from marine and freshwater
Elnaz Azmi   +27 more
doaj   +1 more source

Shape Morphing Using PDE Surfaces [PDF]

open access: yes, 2006
NoA methodology for shape morphing using partial differential equation (PDE) surfaces is presented in this work. The use of the PDE formulation shows how shape morphing can be based on a boundary-value approach by which intermediate shapes can be ...
Gonzalez Castro, Gabriela   +3 more
core  

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