Results 221 to 230 of about 22,621,819 (277)
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Electrokinetic response of granulocytes to concanavalin A and succinyl-concanavalin A
Cell Biophysics, 1981Electrophoretic light scattering has been used to study the effects of concanavalin A (Con A) and succinyl-Con A on the electrophoretic mobility distribution of resident guinea-pig peritoneal eosinophils and human peripheral blood polymorphonuclear leukocytes.
B. R. Ware, Howard R. Petty
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Temperature effects on the concanavalin A molecule and on concanavalin A binding
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1974Abstract Under the same conditions generally used for agglutination tests, the concanavalin A molecule undergoes quarternary structure transitions at different temperatures. The tetrameric form is predominant at 37 °C but it dissociates into dimers as the temperature is lowered.
M. Lonchampt +3 more
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Immunosuppressive Activity of Concanavalin A
Science, 1969Two strains of mice (C-57 B1 and DBA) were given skin allografts from Swiss ICR/HA mice and were treated with varying doses of concanavalin A; the dosage ranged from only two injections of 25 micrograms during the experiment to daily doses of 1000 micrograms intraperitoneally.
G L Gitnick +3 more
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Effect of concanavalin A and succinyl concanavalin A on cytomegalovirus replication in fibroblasts
Archives of Virology, 1986In order to investigate inhibition of viral replication, human embryonic fibroblasts infected with cytomegalovirus (CMV) were treated with 0 to 25 micrograms/ml concanavalin A (Con A) and 0 to 150 micrograms/ml succinylated Con A (S-Con A). Alterations in cellular morphology occurred by day 2 post infection (p.i.) in cultures treated with 10 micrograms/
Mary Norval, Ann Grail
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Concanavalin A as a carrier of daunomycin
Nature, 1977ONE possible approach for increasing the effectiveness of anti-tumour drugs would be to find methods of altering their distribution in the body to increase their local concentration at the tumour cell sites. Ghose et al. have reported the suppression of Ehrlich ascites carcinoma in mice after administration of chlorambucil allegedly bound to anti ...
Kitao, T, Hattori, K
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The luminescence properties of concanavalin A
Biochimica et Biophysica Acta (BBA) - Protein Structure, 19751. The luminescence properties of native concanavalin A, both at room temperature and at 77 degrees K, are similar to those of other proteins containing tyrosine and tryptophan. 2. Binding of methyl alpha-D-glucopyranoside to concanavalin A causes a slight reduction of its fluorescence at room temperature. 3.
J.N. Miller, G.I.C. Nwokedi
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Two-dimensional photonic crystal sensors for visual detection of lectin concanavalin A.
Analytical Chemistry, 2014We fabricated a two-dimensional (2-D) photonic crystal lectin sensing material that utilizes light diffraction from a 2-D colloidal array attached to the surface of a hydrogel that contains mannose carbohydrate groups.
Jian‐Tao Zhang +4 more
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Allergenicity of Concanavalin A in Mice
International Archives of Allergy and Immunology, 1979Concanavalin A (Con A) is a potent allergen in certain strains of mice and in particularly the H-2K<sup>k</sup> mice, A/J, CBA/H, and C3H/He. Using a dose of 100 <i>μ</i>g, the subcutaneous route of injection was the most effective means of inducing high, persistent titers of T cell-dependent circulating anti-Con A reagins ...
Graham F. Mitchell, Adrienne E. Clarke
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Recognition of concanavalin A by cationic glucosylated liposomes.
Langmuir, 2014The specificity of carbohydrate-lectin interaction has been reported as an attractive strategy for drug delivery in cancer therapy because of the high levels of lectins in several human malignancies. A novel cationic glucosylated amphiphile was therefore
A. Mauceri +7 more
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Immunosuppressive Activity of Concanavalin A
International Archives of Allergy and Immunology, 1976Daily intraperitoneal doses of concanavalin A (Con A) produced a dose-related inhibition of adjuvant-induced arthritis in rats. Con A was also effective on established arthritis, markedly relieving the disease after only three doses. The inhibitory effect of Con A was neutralised by pre-incubation with ovalbumin, although this treatment did not modify ...
A K Delitheos, G B West
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