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Factors influencing tissue concentration of vascular endothelial growth factor in colorectal carcinoma

The American Journal of Gastroenterology, 2000
Vascular endothelial growth factor (VEGF) promotes proliferation of various tumor cells by stimulating angiogenesis. Experimentally, hypoxia and energy depletion are known to induce angiogenesis by increasing VEGF expression. We investigated whether factors reflecting the general condition of the patients influence the tissue concentration of VEGF in ...
T, Ono, C, Miki
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A virally inactivated platelet‐derived growth factor/vascular endothelial growth factor concentrate fractionated from human platelets

Transfusion, 2010
BACKGROUND: Human platelet concentrates (PCs) may be a source material to produce purified growth factors (GFs) for clinical use or cell therapy. However, no fractionation process of therapeutic‐grade GF from PCs has ever been developed.STUDY DESIGN AND METHODS: PCs were virally inactivated by solvent/detergent (S/D) treatment, subjected to oil ...
Thierry, Burnouf   +5 more
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Concentrations of epidermal growth factor in mouse milk throughout lactation

Journal of Endocrinology, 1983
A radioimmunoassay was used to measure the concentration of epidermal growth factor (EGF) in mouse milk throughout lactation. The EGF content of mouse milk increased steadily from birth to a concentration of 427 μg/l at day 8 of lactation. These high levels were maintained until the approach of weaning, when values decreased from day 17 to 130 μg/
J M, Beardmore, R C, Richards
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Serum concentrations of basic fibroblast growth factor in collagen diseases

Journal of the American Academy of Dermatology, 1996
Basic fibroblast growth factor (bFGF), a cytoplasmic polypeptide growth regulator that induces endothelial cell and fibroblast proliferation, is produced by endothelial cells and skeletal muscle.We hypothesized that this factor is involved in fibrotic changes in muscle and skin in collagen diseases.The serum level of bFGF was measured in 74 patients ...
T, Kadono   +4 more
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Growth Factor and Interleukin Concentrations in Amniotic Membrane-Conditioned Medium

Current Eye Research, 2016
Application of amniotic membrane-conditioned medium (AMM) eye drops is a potential treatment alternative for therapy-resistant corneal epithelial defects. Our purpose was to determine the concentration of growth factors epidermal growth factor (EGF), nerve growth factor (NGF), vascular endothelial growth factor (VEGF), transforming growth factor β1 ...
Mona, Bischoff   +6 more
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Serum concentrations of epidermal growth factor in human pregnancy

American Journal of Obstetrics and Gynecology, 1973
Abstract A newly measurable peptide, epidermal growth factor (EGF), has been found in pregnant women with the use of a tube radioimmunoassay technique. This peptide appeared to have its highest concentrations during the early part of pregnancy, but measurable quantities were found in the serum throughout the entire course of the gestational period ...
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Thyroxine Increases Nerve Growth Factor Concentration in Adult Mouse Brain

Science, 1979
The effects of thyroxine and propylthiouracil on nerve growth factor concentrations in cerebral cortex, cerebellum, and brainstem of adult male mice were assessed by using a sensitive radioimmunoassay for the β-subunit of mouse nerve growth factor. Thyroxine administration significantly increased the concentration of nerve growth factor in all three ...
P, Walker   +4 more
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Salivary Epidermal Growth Factor Concentration in Adults with Reflux Laryngitis

Otolaryngology–Head and Neck Surgery, 2004
OBJECTIVEThe mechanisms involved in the muco‐sal alterations of laryngopharyngeal reflux (LPR) have not been well established. Reports indicate a decrease in the salivary epidermal growth factor (EGF) of patients with reflux esophagitis, but there are no reports of its behavior in LPR. Our objective was to determine the salivary concentration of EGF in
Claudia A, Eckley   +5 more
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Growth and Product Differentiability as Factors Influencing Changes in Concentration

The Journal of Industrial Economics, 1974
concentration reducing force because smaller firms and potential entrants are encouraged to expand (or enter) during rapid growth periods since they can do so without encroaching on the market of existing firms.' This hypothesis has been examined empirically but the results are conflicting.2 The second hypothesis is that concentration is more likely to
Dalton, James A, Rhoades, Stephen A
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Growth Factor Release during Preparation and Storage of Platelet Concentrates

Vox Sanguinis, 1995
AbstractThe platelet content of platelet‐derived growth factor (PDGF), a mitogen stored in the alpha‐granules, was studied during preparation and storage of platelet concentrates (PC) and compared to the growth‐promoting activity of platelets, β‐thromboglobulin (β‐TG) and lactate dehydrogenase (LD).
E, Ledent, A, Wasteson, G, Berlin
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