Results 81 to 90 of about 15,789,920 (107)

Epigenetic compartmentalization of mitotic chromosomes by phase-separation-driven repulsion between WDR5 and the chromosomal passenger complex. [PDF]

Nat Commun
Wang Y, Jiang X, Liu X, Jiang X, Wang X, Song X, Chen F, Liu Y, Gou XZ, Tang AH, Sheng S, Yao X, Hou Z, Liu D.   +13 more
europepmc   +1 more source

Mechanism of K63-linked polyubiquitin recognition and cleavage by the BRCA1-A complex. [PDF]

Nat Commun
Foglizzo M, Datta A, Degtjarik O, Perera H, Liburd J, Sykora UM, Ganji SR, Wildsmith G, Chandler F, Campbell LJ, Calabrese AN, Greenberg RA, Zeqiraj E.   +12 more
europepmc   +1 more source

Discovery of molecular glues that bind FKBP12 and structurally distinct targets using DNA-encoded libraries. [PDF]

Nat Commun
Zandi TA, Romanowski MJ, Viscomi JS, Gunderson K, Tan ZY, Tong B, Bonazzi S, Zécri FJ, Schreiber SL, Michaud GA.   +9 more
europepmc   +1 more source

Structure-Guided Optimization of Novel Inhibitors of <i>Plasmodium</i> Lysyl-tRNA Synthetase with Multistage Activity against Malaria Parasites. [PDF]

J Med Chem
Forte B, Bellany F, Campbell PS, Chemi G, Dawson A, Anderson M, Aniweh Y, Burkhard AY, Aguiar ACC, Churchyard A, Cooper CA, Dos Santos Ferreira A, Famodimu MT, Fang FG, Hu X, Huijs T, Baud D, Jansen C, Jiménez Díaz MB, Bonnert R, Boyd S, Crespo-Fernández B, Mitasev B, Montagna S, Mok S, Murugesan D, Narwal SK, Norcross NR, Okombo J, Park H, Peet C, Pereira DB, Post JM, Reader J, Riley J, Robinson DA, Shinkyo R, Simeons FRC, Simpson L, Smith A, Smith D, Striepen J, Teles CBG, van der Laak R, Uhlemann AC, Vantaux A, Wilson C, Witkowski B, Wood G, Yeo T, Zuccotto F, Angulo-Barturen I, Baum J, Bolscher JM, Guido RVC, Birkholtz LM, Delves MJ, Dembele L, Fidock DA, Gamo FJ, Kyle DE, Maher SP, Popovici J, Walpole C, Gusovsky F, Willis PA, Read KD, Gilbert IH, Baragaña B.   +68 more
europepmc   +1 more source

Differentiating 5-Thiooxazoles from Oxazolone-Coupled Thioamides in RiPP Natural Products. [PDF]

J Nat Prod
Manley OM, Shriver TJ, Ayala JM, Owen BC, Ziarek JJ, Rosenzweig AC.   +5 more
europepmc   +1 more source

The DNMT1 CXXC domain senses CpG islands for DNA methylation inhibition. [PDF]

Nat Commun
Fang J, Pan B, Ren W, Lu J, Zhao T, Guo Y, Cai L, Wang Y, Wang GG, Song J.   +9 more
europepmc   +1 more source

Structural basis of specific lysine transport by Pseudomonas aeruginosa permease LysP. [PDF]

Nat Commun
Bicer D, Matsuoka R, Moumbock AFA, Sukumar P, Suades A, Cheruvara H, Quigley A, Drew D, Pardon E, Steyaert J, Henderson PJF, Caffrey M, Griese JJ, Nji E.   +13 more
europepmc   +1 more source