Results 121 to 130 of about 3,531,413 (264)

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

The Compact Embeddings and the Concentration-Compactness Principles for Anisotropic Variable Exponent Sobolev Spaces and Applications

The Journal of Geometric Analysis
Abstract In this paper, we present new results about the compact embeddings of anisotropic variable exponent Sobolev spaces into variable Lebesgue spaces. We also refine and extend the concentration–compactness principle to trace embeddings in these spaces.
Nabil Chems Eddine, Maria Alessandra Ragusa   +1 more
openaire   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Several versions of the compensated compactness principle

, 2011
Pastukhova SE, Khripunova Balci A. Several versions of the compensated compactness principle. Sbornik: Mathematics.
Khripunova Balci, Anna ; https://orcid.org/, Svetlana E Pastukhova, Anna S Khripunova, Pastukhova, Svetlana E   +3 more
core   +1 more source

Concentration-compactness principle and applications to nonlocal elliptic problems

, 2016
The main goal of this work is to analyze concentration-compactness principles for fractional Sobolev spaces based on the concentration compactness principle of P.-L. Lions and in the pro le decomposition for weak convergence in Hilbert spaces due to K.
Souza, Diego Ferraz de
core   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Existence of positive solutions for Brezis-Nirenberg type problems involving an inverse operator

Electronic Journal of Differential Equations, 2021
Pablo Alvarez-Caudevilla, Eduardo Colorado, Alejandro Ortega   +2 more
doaj  

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Existence of normalized solutions to Kirchhoff-Boussinesq equations in the subcritical and supercritical regime

Electronic Journal of Differential Equations
In this article we study the existence of normalized solutions to the Kirchhoff-Boussinesq equation under the mass constraint $\|u\|_{2}=c$. In the $L^{2}$-subcritical regime, we apply Ekeland's variational principle and concentration compactness method ...
Chunling Tao, Lintao Liu, Kaimin Teng
doaj