Results 51 to 60 of about 32,890 (279)

Existence and multiplicity of solutions for fractional Schödinger equation involving a critical nonlinearity

open access: yesAdvances in Difference Equations, 2019
In this paper, we investigate the fractional Schödinger equation involving a critical growth. By using the principle of concentration compactness and the variational method, we obtain some new existence results for the above equation, which improve the ...
Yongzhen Yun, Tianqing An, Guoju Ye
doaj   +1 more source

Existence and stability of solitons for the nonlinear Schr\"odinger equation on hyperbolic space

open access: yes, 2014
We study the existence and stability of ground state solutions or solitons to a nonlinear stationary equation on hyperbolic space. The method of concentration compactness applies and shows that the results correlate strongly to those of Euclidean space ...
Berestycki H   +6 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Existence of solutions to quasilinear elliptic systems with combined critical Sobolev-Hardy terms

open access: yesElectronic Journal of Differential Equations, 2012
This article is devoted to the study of multiple positive solutions to a singular elliptic system where the nonlinearity involves a combination of concave and convex terms.
Nemat Nyamoradi, Mohamad Javidi
doaj  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

open access: yesFEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Home - About - Disclaimer - Privacy