Results 51 to 60 of about 33,828 (297)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Concentration compactness principles for the systems of critical elliptic equations [PDF]
Differential Equations & Applications, 2012 In this paper, some important variants of the concentration compactness principle are established. By the variants, some kinds of the elliptic systems can be investigated and the existence of nontrivial solutions to the systems can be verified by the variational methods.
openaire +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Concentration-compactness at the mountain pass level in semilinear elliptic problems
, 2007 The concentration compactness framework for semilinear elliptic equations without compactness, set originally by P.-L.Lions for constrained minimization in the case of homogeneous nonlinearity, is extended here to the case of general nonlinearities in ...
TIntarev, Kyril
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Concentration-compactness principle for variable exponent spaces and applications
Electronic Journal of Differential Equations, 2010 In this article, we extend the well-known concentration - compactness principle by Lions to the variable exponent case. We also give some applications to the existence problem for the p(x)-Laplacian with critical growth.
Julian Fernandez Bonder, Analia Silva
doaj
On a study and applications of the Concentration-compactness type principle for Systems with critical terms in $\mathbb{R}^{N}$ [PDF]
, 2022 Lauren Maria Mezzomo Bonaldo +2 more
openalex +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Existence of maximizers for Hardy-Littlewood-Sobolev inequalities on the Heisenberg group [PDF]
, 2013 In this paper, we investigate the sharp Hardy-Littlewood-Sobolev inequalities on the Heisenberg group. On one hand, we apply the concentration compactness principle to prove the existence of the maximizers. While the approach here gives a different proof
Han, Xiaolong
core