Results 51 to 60 of about 31,246 (265)

Combining transient dynamics and logistic‐asymptotic growth to study the recovery of two seabird populations after rat eradication

Population Ecology, EarlyView.
This study examines the demographic dynamics of two seabird populations on Tromelin Island, 15 years after the eradication of brown rats. The results indicate that these populations are in good health and are expected to continue growing until breeding sites are saturated in about a century.
Merlène Saunier, Christophe Barbraud, Maxime Amy, Sabine Orlowski, Jean Hivert, Gabrielle Dicque, Matthieu Le Corre   +6 more
wiley   +1 more source

A multiplicity result for the scalar field equation

, 2013
We prove the existence of $N - 1$ distinct pairs of nontrivial solutions of the scalar field equation in ${\mathbb R}^N$ under a slow decay condition on the potential near infinity, without any symmetry assumptions.
Perera, Kanishka
core   +1 more source

The concentration-compactness principles for W ^s,p(·,·)(ℝ ^N ) and application [PDF]

Advances in Nonlinear Analysis, 2020
Abstract We obtain a critical imbedding and then, concentration-compactness principles for fractional Sobolev spaces with variable exponents. As an application of these results, we obtain the existence of many solutions for a class of critical nonlocal problems with variable exponents, which is even new for constant exponent case.
Ky Ho, Yun-Ho Kim
openaire   +3 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Multiple solutions for a critical $p(x)$-Kirchhoff type equations

Boletim da Sociedade Paranaense de Matemática, 2019
In this paper, by using the concentration--compactness principle of Lions for variable exponents and variational arguments, we obtain the existence and multiplicity solutions for a class of $p(x)$-Kirchhoff type equations with critical exponent.
Najib Tsouli, Mustapha Haddaoui, El Miloud Hssini   +2 more
doaj   +1 more source

Generalized Concentration-Compactness Principles for Variable Exponent Lebesgue Spaces with Asymptotic Analysis of Low Energy Extremals [PDF]

Mathematics, 2020
In this paper, we prove two generalized concentration-compactness principles for variable exponent Lebesgue spaces and as an application study the asymptotic behaviour of low energy extremals.
Zia Bashir, Juan Luis García Guirao, Adil Siddique, Tareq Saeed   +3 more
openaire   +3 more sources

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source